摘要
目的建立稳心颗粒制剂的鉴定分析新方法。方法采用X射线衍射傅里叶(Fourier)指纹图谱法。结果对1个稳心颗粒样品进行试验,获得了其X射线衍射傅里叶指纹图谱及特征标记峰值。结论 X射线衍射傅里叶指纹图谱法可用于稳心颗粒的鉴定分析。
Objective：To explore effects of low does of tilofiban in conservative treatment of elderly patients with non-ST-segment acute coronary syndromeis（NSTEACS）.Method：The 96elderly patients with diagnosed NSTEACS were divided into control group（n=46）and observation group（n=50）.All patients were given aspirin,clopidogrel and low molecular heparin.The observation group was added low does tilofiban after admission to hospital on the basis of conventional drug therapy.We compared the efficacy and adverse reactions between the two groups.Result：Compared with the control group,After 7dand 30d,the incidence of composite cardiovascular events（refractory angina pectoris,myocardial infarction again and death）in the observation group were all reduced（P0.05）.Platelet aggregation rate in observation group was decreased more obvious（P0.01）.The major adverse events in control group and observation group were bleeding,the incidence was 4.35% and 6.0% respectively（P0.05）.Conclusion：In the non-interventional therapy in elderly patients with NSTEACS,low dose of tilofiban can effectively strengthen the antiplatelet effect witout increased risk of bleeding.And it is safe and effective to shared with aspirin,clopidogrel,and low molecular heparin.
出处
《中国药业》
CAS
2014年第2期31-33,共3页
China Pharmaceuticals
