摘要
目的观察引起ICU呼吸机相关性肺炎相关因素,探讨呼吸机相关性肺炎预防对策。方法回顾性分析2005年10月-2012年9月180例ICU患者应用呼吸机治疗患者的临床资料,统计呼吸机相关性肺炎发生率,观察呼吸机相关性肺炎与相关因素的相关性。结果 180例患者发生呼吸机相关性肺炎40例,发生率22.22%,logistic回归分析引起呼吸机相关性肺炎的危险因素包括:胃内容物反流、血清白蛋白水平低、呼吸机应用时间长、抗酸剂、广谱抗菌药物的应用,发生率分别为36.96%、31.46%、38.16%、25.74%、23.74%,OR值分别为5.45、4.13、3.39、3.23、2.98。结论 ICU呼吸机相关性肺炎发生率较高,影响因素复杂,应给予半卧位、改善全身状态加强营养支持、严格执行抗菌药物的使用原则、避免预防性常规应用强制酸剂、缩短呼吸机应用时间,减少呼吸机相关性肺炎的发生。
OBJECTIVE To observe the related risk factors for ventilator-associated pneumonia（VAP）in the ICU and explore prevention countermeasures for VAP.METHODS The clinical data of 180patients who underwent mechanical ventilation in the ICU were retrospectively analyzed,then the incidence of VAP was taken for statistics, and the related risk factors for the VAP were observed.RESULTS Of totally 180patients investigated,the VAP occurred in 40cases with the incidence rate of 22.22%.The logistic regression analysis showed that the risk factors for VAP included the regurgitation of gastric contents,low level of serum albumin,prolonged use of breathing machine,and use of antacid or broad-spectrum antibiotics,the incidence rates were 36.96%,31.46%, 38.16%,25.74%,and 23.74%,respectively,and the OR values were 5.45,4.13,3.39,3.23,and 2.98,respectively.CONCLUSIONThe incidence of VAP is high in the ICU,and the influencing factors are complex;it is necessary to give semirecumbent position,improve the body condition,strengthen the nutritional support,rigidly execute the principles of use of antibiotics,avoid prophylactic use of acids,and shorten the mechanical ventilation duration so as to reduce the incidence of VAP.
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2014年第1期110-111,121,共3页
Chinese Journal of Nosocomiology
基金
浙江省自然科学基金青年基金项目(LQ12H01002)
关键词
ICU
呼吸机相关性肺炎
影响因素
预防对策
ICU
Ventilator-associated pneumonia
Influencing factor
Prevention countermeasure
