摘要
目的系统评价呼吸机管道更换时间与呼吸机相关性肺炎(VAP)发生的相关性。方法应用计算机检索近10年的Pubmed电子数据库、中国生物医学文献数据库和中国期刊全文数据库,对符合标准的文献按Cochrane协作网推荐的方法进行Meta分析。结果共纳入10项研究,17419例病例。按呼吸机管道更换时间分为1 d组191例、2 d组9448例、3 d组174例和7 d组7606例。Meta分析结果显示,7 d组的VAP发生率与1 d组、2 d组和3 d组比较,差异均无统计学意义(RR分别为2.40、1.40和0.81;95%CI分别为0.61～9.47、0.97～2.03和0.51～1.30;P值分别为0.21、0.07和0.39)。结论呼吸机管道每7 d更换一次较为合理,有利于节省人力、物力,而并不增加VAP的发生率。
【Objective】 To evaluate the association of the ventilator circuit change interval with the incidence of ventilator-associated pneumonia（VAP）.【Methods】 The related literatures and studies were searched out from the following electronic bibliographic databases： PubMed（2000 to October 2010）,China Biological Medicine Database（2000 to October 2010） and Chinese Journals Full-text Database（2000 to October 2010）.The Cochrane Collaboration＇s RevMan 4.2 was used for Meta-analysis.【Results】 Total ten control trials involving 17419 patients were included.These patients were divided into four groups according to different ventilator circuit change intervals.They were the 1 day group（n =191）,the 2 days group（n =9448）,the 3 days group（n =174） and the 7 days group（n =7606）.Results of Meta-analysis indicated that the VAP incidence in the 7 days group had no statistically significant difference when compared with those in the 1 day group,the 2 days group or the 3 days group,with the RR values of 2.40,1.40 and 0.81,the 95% CIs of 0.61～9.47,0.97～2.03 and 0.51～1.30,and the P values of 0.21,0.07 and 0.39 respectively.【Conclusion】 To replace the ventilator circuit every 7 days is reasonable,which can save manpower and material resources but not increase the VAP incidence.
出处
《中国现代医学杂志》
CAS
CSCD
北大核心
2011年第12期1471-1475,共5页
China Journal of Modern Medicine
关键词
呼吸机相关性肺炎
呼吸机管道更换
META分析
ventilator-associated pneumonia
ventilator circuit change interval
Meta-analysis
