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替米沙坦治疗中重度老年性高血压的临床疗效分析 被引量:2

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摘要 目的探讨替米沙坦治疗老年高血压的临床价值和用药安全性。方法将本院50例原发性高血压老年患者随机分成2组,观察组25例和对照组25例,对照组口服贝那普利,观察组在对照组治疗方案基础上联合使用替米沙坦,以4周为1个疗程,监测患者治疗前后的血压、心率、血常规、尿常规、肝肾功能,并且记录患者服药期间产生的不良反应。结果治疗4周后2组患者的舒张压和收缩压均有下降,治疗前后数值具有统计学差异(P<0.05)。其中观察组总有效率为92%,对照组总有效率为80%,两组具有统计学差异(P<0.05),观察组优于对照组。结论替米沙坦对原发性高血压具有理想的临床疗效,临床上建议进一步推广。
出处 《中国医药指南》 2013年第35期494-495,共2页 Guide of China Medicine
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  • 1王海燕.肾脏病学[M].3版.北京:人民卫生出版社,2008:1815-1816.
  • 2Romano N,Marico V,Enrico B,et al.Course of renal function type 2 diabetic patients with abnormalities of burnin excretion rate[J].Diabetes,2000,49(3):476-484.
  • 3Jerums G,Allen TJ,Campbell,et al.Long-term comparison between perindopril and nifedipine in normotensive patients with type I diabetes and microalbuminuria[J].Am J Kidney Dis,2001,37(5):890-899.
  • 4Obata J,Nakamura T,Kuroyanaga R,et al.Candesartan prevents the progression of glomerulosclerosis in genetic hypertensive rats[].Kidney International.1997
  • 5Hunsicker LG,Atkins RC,Lewis JB,et al.Impact of irbesartan,blood pressure control,and proteinuria on renal outcomes in the lrbesartan Diabetic NephropathyTrial[].KidneyInt Supp.2004
  • 6Nskao N,Yoshimura A,Morita H,et al.Combination therapy of an-giotensin-Ⅱreceptor blocker and angiotensin-converting-enzyme in-hibitor in non-diabetic renal disease(COOPERATE):a randomised con-trolled trial[].The Lancet.2003
  • 7Leenen FH,Yuan B.Prevention of hypertension by irbesartan in dahl S rats relates to central angiotensin II type I receptor blockade[].Journal of Hypertension.2001
  • 8Shahinfar S,Simpson RL,Carides AD et al.Safety of losartan in hypertensive patients with thiazide - induced hyperuricemia[].Kidney International.1999
  • 9Brenner BM,Cooper ME,Zeeuw D,et al.Effects of losartan on renal and cardiovascular outcomes in patients with type 2 diabetes and nephropathy[].New England Journal of Medicine The.2001
  • 10Parving HH,Lehnert H,Brochner-Mortensen J,et al.The effect of irbesartan on the development of diabetic nephropathy in patients with type 2 diabetes[].The New England Journal of Medicine.2001

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