摘要
目的探讨经尿道等离子汽化电切术联合术后吡柔比星膀胱灌注治疗腺性膀胱炎的临床疗效。方法对32例腺性膀胱炎患者在腰硬联合麻醉下行经尿道等离子汽化电切术;术后根据具体病情留置尿管5～7d,拔管前以化疗药物吡柔比星行膀胱灌注治疗,每周1次,共8次,后每月1次,连续10次。每3～6个月复查膀胱镜,观察膀胱黏膜情况,并选择性复查膀胱黏膜组织活检。结果 32例均手术成功,术中无严重出血和膀胱穿孔、水中毒等并发症发生,术后尿路刺激等症状均明显改善。术后随访4～36个月,23例治愈,6例好转,有效率90.6%;3例于术后6～10个月复发,复发者均再次行经尿道等离子汽化电切治疗。随访期间1例出现较严重的尿频、尿急、尿痛等膀胱刺激症,2例出现淡红色肉眼血尿,未发现恶变病例,无其他并发症。结论经尿道等离子汽化电切术联合术后吡柔比星膀胱灌注治疗具有安全、并发症少、疗效确切等优点,是治疗腺性膀胱炎的有效方法。
Objective To evaluate the clinical efficacy of plasmakinetic superpulse transurethral resection combined with postoperative pirarubicin bladder irrigation in cystitis glandularis. Meth- ods Thirty-two patients with cystitis glandularis underwent plasmakinetic superpulse transure- thral resection under combined spinal-epidural anesthesia. Postoperative indwelling catheters were used for 5-7 days. Before extubation, patients were given pirarubiein bladder irrigation 8 times once per week, followed by pirarubicin bladder irrigation 10 times once per month. In addi- tion, cystoscopy and biopsy were performed every 3-6 months to observe the bladder mucosa. Re- sults All operations were performed successfully without serious complications such as bleeding, bladder perforation and water intoxication. Furthermore, postoperative urinary irritation symp- toms were significantly improved. After follow-up for 4-36 months, 23 of the 32 patients were cured and 6 achieved improvement. The effective rate was 90. 6%. Three patients underwent plasmakinetic superpulse transurethral resection again due to the recurrence 6-10 months after op- eration. During the follow-up period, 1 patient had serious bladder irritation symptoms such as frequency, urgency and dysuria, and 2 patients had reddish gross hematuria. No malignant trans-formation and other complications were found. Conclusion Plasmakinetic thral resection combined with results in fewer complications postoperative pirarubicin bladder irrigation is in the treatment of cystitis glandularis. superpulse transure- safe and effective and results in fewer complications in the treatment of cystitis glandularis.
出处
《南昌大学学报（医学版）》
CAS
2013年第7期19-21,共3页
Journal of Nanchang University：Medical Sciences
关键词
腺性膀胱炎
经尿道等离子汽化电切术
吡柔比星
膀胱灌注
cystitis glandularis
plasmakinetic superpulse transurethral resection
pirarubicin
bladder irrigation
