摘要
目的探讨经尿道汽化电切术联合膀胱化疗药物灌注治疗腺性膀胱炎的临床疗效。方法回顾性分析2005年1月-2007年8月收治的138例经病理证实的腺性膀胱炎患者的临床资料,临床表现以膀胱刺激症状+镜下血尿为主,膀胱镜检查表现为滤泡样、绒毛样、苔藓样改变。106例(以下称灌注组)行经尿道汽化电切术后1月采用丝裂霉素或吡柔比星膀胱灌注,治疗方案为每周1次,共6次,术后定期行尿常规和膀胱镜检查。32例(以下称未灌注组)术后因经济原因未做灌注。结果随访3-30个月,灌注组74例症状消失,22例好转,9例症状未见明显改善,复发1例,阳性率为90.7%;未灌注组14例症状消失,4例好转,6例症状未见明显改善,复发8例,阳性率为56.3%,两组均无恶变病例。两组比较差异有显著性(χ2=20.147,P<0.01)。结论经尿道汽化电切术联合膀胱灌注化疗药物治疗腺性膀胱炎具有较好的疗效,并能有效地预防其复发。
Objective To evaluate the clinical efficacy of transurethral electrovaporization and bladder irrigation with chemo- therapy in the treatment of cystitis glandularis . Methods 138 cases of cystitis glandularis which diagnosed by pathology were retrospective study between January 2005 and August 2007. Clinical displayed micturition and urgency with hematuria. Cystoscopic examination displayed follicular orvillous and lichen lomatous change. Transurethral electrovaporization was performed. 106 cases received mitomycinc or pirarubicin bladder irrigation four weeks after surgery,once a week for 6 weeks. And 32 cases were not performed irrigation for economic. The cystoscopy was periodically performed during following - up. Results During the 15 months following - up （ ranging 3 - 30 months） ,74cases fully recovered,22 cases had turned for better,9 cases had failed, 1 cases relapse. 32 cases were not performed irrigation, 14eases fully recovered,4 eases had turned for better,6 cases had failed,and 8 cases relapse. There was no case developed adenocarcinoma in two groups. The two groups had significant statistical differentiation in positive rate（ X^2 = 20. 147 ,P 〈 0. 01 ）. Conclusion Transurethral eleetrovaporization combined with irrigation of bladder with mitomyeine or pirarubicin is effective for cystitis glandularis, and it can prevent cystitis glandularis from developing into adenocarcinoma.
出处
《宁夏医学杂志》
CAS
2008年第5期411-412,共2页
Ningxia Medical Journal
关键词
腺性膀胱炎
汽化电切
膀胱灌注
Cystitis glandularis
Transurethral electrovaporization
Irrigation of bladder
