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自拟淸胆化瘀汤治疗老年胆囊癌的临床研究 被引量:4

Clinical Observation on Self-made Qingdan HuayuDecoction in Treatment of Gallbladder Carcinoma in Old Patients
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摘要 目的:观察淸胆化瘀汤联合化疗对胆囊癌的临床疗效。方法:采用随机法将40例胆囊癌患者分为治疗组(淸胆化瘀汤+化疗)20例、对照组(化疗)20例,比较两组临床完成情况、近期客观疗效、治疗前后临床症状、生活质量卡氏评分、体重、免疫功能(NK细胞)的变化和毒副反应情况。结果:治疗组较对照组可提高有效率、较好改善部分临床症状,稳定并增加体重,提高患者生存质量,保护机体免疫功能,减轻化疗毒副反应(P<0.05);但在稳定病灶方面无显著性差异(P>0.05)。结论:淸胆化瘀汤联合化疗对胆囊癌有较好的临床效果。 Objective:To investigate the clinical effect of Qingdan Huayu Decoction combined with chemotherapy on gallbladder carcinoma. Methods :40 cases of gallbladder cancer patients were randomly allocated into two groups : the treat- ment group( Qingdan Huayu Decoction + chemotherapy) with 20 cases, and the control group(chemotherapy) with 20 ca- ses. The completion situation of clinical works, the response rates, the clinical symptoms before and after treatment, Karnofsky score of quality life, body weight, immune function ( NK cells) changes and adverse reactions were compared between two groups. Results : The treatment group can improve the efficiency, partly improve clinical symptoms, stabilize and increase weights, improve patients quality life, protect the immune function, and reduce the adverse reactions of chemotherapy than the control group ( P 〈 0. 05 ) ; but there was no significant difference in stable lesions ( P 〉 0.05 ). Conclusion:Qingdan HuayuDecoction combined with chemotherapy has better clinical effects on gallbladder carcinoma.
作者 张亚密
出处 《中华中医药学刊》 CAS 2013年第8期1810-1812,共3页 Chinese Archives of Traditional Chinese Medicine
关键词 淸胆化瘀汤 卡培他滨 胆囊癌 Qingdan Huayu Decoction capecitabine gallbladder carcinoma
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  • 1中华人民共和国卫生部医政司.中国常见恶性肿瘤诊治规范[S].2版.北京:北京医科大学中国协和医科大学联合出版社,1996:16-19.
  • 2DOVAL DC, GUPTA SK, AWASTHY BS, et al. Survival and treatment trends in gall bladder cancer- a retrospective study of 117cases of gall bladder cancer from 2 centers in India[ J]. Proc Am Soc Clin Oncol, 2003, 22: 1237a.
  • 3金云洁,黄晓东,沈清,朱纪华,姚晓祥.射频热疗联合卡培他滨治疗晚期胆囊癌[J].中国医学工程,2007,15(11):932-934. 被引量:2

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