摘要
甲状腺癌是内分泌系统常见的肿瘤之一,不同病理类型的甲状腺癌的生物学行为及预后迥异。近年来,分子核医学已在甲状腺癌的诊断、治疗方面取得了重要的研究进展。结合新的显像剂及SPECT/CT、PET/CT等显像设备的应用,分子核医学可实现在细胞和分子水平上定性和定量显示甲状腺癌特定分子的表达及其水平的变化,并可实现靶向治疗。本文综述了国内外有关分子核医学在甲状腺癌影像诊断及靶向治疗中的应用进展。
Thyroid carcinoma is the most common malignancy of endocrine system. Different pathological classifications of thyroid carcinoma differ greatly in biological behavior and prognosis. As a newly-emerging subject, molecular nuclear medicine has made rapid ad- vances in both diagnosis and treatment of thyroid carcinoma. With the application of new imaging agents and devices such as SPECT/CT and PET/CT, molecular nuclear imaging can demonstrate, both qualitatively and quantitatively, the alterations in specific molecules of thyroid cancer on cellular and molecular level. Meanwhile, it is capable of utilizing radio-pharmaceuticals to target specifically to these molecules. Here we present a review on the latest progresses in this field.
出处
《同位素》
CAS
2013年第2期115-121,共7页
Journal of Isotopes
关键词
甲状腺癌
分子核医学
靶向治疗
thyroid cancer
molecular nuclear medicine
targeted treatment
