摘要
对生物性骨载体 (Biological Bone Carrier,BBC)的制备方法、成分分析、动物体内植入试验、生物力学强度、超微结构、交叉抗原性、临床应用等一系列研究做了详尽的报道 ,阐述了为尽量降低 BBC抗原性而采取综合处理方法的合理性 ,并分析归纳出 BBC作为骨替代材料的优点 :(1)良好的生物相容性 ;(2 )合适的力学强度 ;(3)天然的多孔结构和合适的孔隙率 ;(4)能为宿主吸收替代 ;(5 )来源广泛 ,加工贮存方便 ;(6 )吸附 BMP后同时发挥骨诱导和骨传导作用。
A series of studies on biological bone carrier (BBC), including preparation methods, components analysis, animal implantation test, biomechanical strength, ultrastructure, cross antigenicity and clinical application are reported in this article. Comprehensive process was adopted to reduce the antigen of BBC. As a substitute for bone, BBC has the following merits:(1)good biocompatibility;(2)suitable mechanical strength;(3)natural porous structure and porosity;(4)absorbability and replaceability in host;(5)unlimited sources, ready availability and simplicity in process and storage;(6)both functions of osteoconductability and osteoinductability can be developed after BBC combined with BMP.
出处
《生物医学工程学杂志》
EI
CAS
CSCD
北大核心
2000年第3期346-347,353,共3页
Journal of Biomedical Engineering
基金
国家自然科学基金!资助项目 ( 3 9160 0 75 )
卫生部科学研究基金资助项目 !( 913 0 2 2 2 9)
