摘要
目的探讨冠状动脉粥样硬化性心脏病(CAHD)患者血电解质紊乱的特点及其与CAHD危险因素的相关性。方法 474例疑似CAHD患者根据冠状动脉造影结果分为CAHD组278例和对照组196例(无冠状动脉粥样硬化改变),对比2组患者血Na+、K+、Ca2+和Mg2+水平,分析CAHD组患者血Na+、K+、Ca2+和Mg2+水平与CAHD易患因素的相关性。结果 CAHD组患者血Na+和Ca2+水平显著高于对照组(P<0.01),血K+和Mg2+水平显著低于对照组(P<0.01)。CAHD组患者CAHD易患因素发生率显著高于对照组(P<0.05,P<0.01)。CAHD患者的血Na+和Ca2+水平与高血压呈正相关(P<0.05),血K+和Mg2+水平与高血压呈负相关(P<0.05);CAHD患者的血Na+、K+和Ca2+水平与糖尿病呈负相关(P<0.05),血Mg2+水平与糖尿病呈正相关(P<0.05);血Na+、K+和Ca2+水平与血脂异常呈正相关(P<0.05),血Mg2+水平与血脂异常呈负相关(P<0.05);血Na+、K+、Ca2+和Mg2+水平与高血压并发糖尿病均呈正相关(P<0.05);血Na+、K+和Ca2+水平与高血压并发血脂异常呈正相关(P<0.05),血Mg2+水平与高血压并发血脂异常呈负相关(P<0.05);血Na+、K+、Ca2+和Mg2+水平与糖尿病并发血脂异常均呈正相关(P<0.05);血Na+、K+、Ca2+和Mg2+水平与高血压并发糖尿病和血脂异常呈正相关(P<0.01)。结论 CAHD患者存在电解质紊乱,CAHD患者电解质紊乱与CAHD易患因素有相关性。
Objective To explore the clinical feature of electrolyte disturbances and the association between electrolyte disturbances and the risk factors for patients with coronary atherosclerotic heart disease （CAHD）. Methods A total of 474 pa- tients with suspected CAHD were divided into CAHD group（ n = 278 ） and control group（ 196 patients without CAHD） accord- ing to the results of coronary arteriongraphy. The levels of serum Na ^＋ , K ^＋ , Ca2 ＋ and Mg2＋ were compared between the two groups ;the associations of serum Na ^＋ , K ^＋ , Ca2 ^＋ and Mg2 ^＋ levels and the risk factors for CAHD were analyzed. Results Compared with control group ,the levels of serum Na ^＋ and Ca2＋ in CAHD group were significantly higher（ P 〈 0.01 ） ,but the levels of serum K ＋ and Mg2^＋ in CAHD group were significantly lower（ P 〈 0.01 ）. The risk factors incidences in CAHD group were significantly higher than those in control group （ P 〈 0.05 or P 〈 0.01 ）. The serum Na ＋ and Ca2 ＋ levels were positively correlated to hypertension in patients with CAHD（ P 〈 0.05 ） , the serum K ＋ and Mg2 ＋ levels were negatively correlated to hy- pertension in patients with CAHD （P 〈 0. 05 ）. The serum Na ＋ , K ^＋ and Ca2＋ levels were negatively correlated to diabetes in patients with CAHD（ P 〈 0.05 ）, but the serum Mg^2＋ level was positively correlated to diabetes in patients with CAHD （P 〈 0. 05）. The serum Na^＋ ,K^＋ and Ca^2＋ levels were positively correlated to dyslipidemia（P 〈0.05） ;but the serum Mg^2＋ level was negatively correlated to dyslipidemia（ P 〈 0.05 ）. The serum Na ^＋ , K ＋ , Ca^2＋ and Mg^2＋ levels were positively correlated to hypertension combined with diabetes（ P 〈 0.05 ）. The serum Na ＋ , K ^＋ and Ca^2＋ levels were positively correlated to hyperten- sion combined with dyslipidemia（ P 〈 0.05 ） ; but the serum Mg： ＋ level was negatively correlated to hypertension combined with dyslipidemia （P 〈 0.05 ）. The serum Na^ ＋ , K^ ＋ , Ca^2＋ and Mg^2＋ levels were positively correlated to diabetes combined with dyslipidemia（ P 〈 0.05 ）. The serum Na ^＋ , K^ ＋ , Ca^2＋ and Mg^2＋ levels were positively correlated to hypertension combined with di- abetes and dyslipidemia（P 〈 0.01 ）. Conclusion Electrolyte disturbances may exist in patients with CAHD, the electrolyte disturbances is related to the risk factors for CAHD.
出处
《新乡医学院学报》
CAS
2013年第5期398-400,共3页
Journal of Xinxiang Medical University
