摘要
线栓法大鼠大脑中动脉阻塞(MCAO)模型被普遍认为是脑缺血标准动物模型。该模型在制备过程中,易受到多重因素的影响。文章从血管解剖位置、插线的制备、切口位置、插线深度及翼腭动脉结扎等角度,对模型塑造过程中发现的现象与问题进行论述。
Middle cerebral artery occlusion model with suture-occluded mechod in rats is considered to be the standard ani- mal model of cerebral ischemia. In the process of preparation,it is susceptible to be influenced by multiple factors. This article discussed the phenomenon and problems discovered in the modeling process, such as vascular anatomic location, preparation of line bolt, incision position, depth of line inserted and ligation of the pterygopalatine artery.
出处
《辽宁中医杂志》
CAS
2013年第1期21-23,共3页
Liaoning Journal of Traditional Chinese Medicine
基金
国家自然科学基金面上项目(30973708)
关键词
线栓法
大鼠
大脑中动脉阻塞模型
suture-occluded method
rats
middle cerebral artery occlusion model