摘要
目的评估徐州地区无偿献血者血液安全状况，以预防和控制临床经输血传播疾病的发生。方法统计2007～2011年无偿献血者血液丙氨酸氨基转移酶（ALT）、HBsAg、抗-HCV、抗-HIV、抗-TP检测不合格结果，并进行回顾性调查分析。结果无偿献血者血液总的不合格率为3．19％，分项指标ALT、HBsAg、抗-HCV、抗-HIV、抗-TP不合格率分别为2．13％、0．28％、0．33％、0．12％和0．37％；各年不合格率比较除抗-TP（P〉0．05，x2=5．76）外，其他项目ALT、HBsAg、抗-HCV和抗-HIV，P均〈0．05（x2分别为1662．75、69．37、2070．16和11．09），且采血前是否筛查ALT其差异具有统计学意义（P〈0．05，x2=940．75）。结论采血前进行ALT的筛查，可显著降低血液检测不合格率，同时ALT不合格亦是造成血液报废的主要原因；另外我市HIV感染率呈逐年上升趋势，因此发展固定献血者，从低危人群中采集血液是保证血液安全的基本策略。
Objective To evaluate blood safety of unpaid blood donors in Xuzhou area and prevent and control the occurrence of clinical transfusion - transmitted diseases. Methods Retrospective investigation and analysis of unquali- fied results of blood ALT, HBsAg, anti - HCV, anti - HIV, anti - TP of unpaid blood donors in 2007 - 2011. Results The blood total unqualified rate of unpaid blood donors was 3.19%. The blood ALT, HBsAg, anti - HCV, anti - HIV, anti - TP unqualified rates were 2.13% , 0.28% , 0.33% , 0.12% and 0.37% respectively. There was no significant difference for unqualified rate of anti - TP （ P 〉 0.05 ）. There cvas significant difference for unqualified rate of the other items （ P 〈 0.05 ）. The difference was statistically significant whether ALT was screened before blood sampling （ P 〈 0.05 ）. Conclusions Blood ALT inspection before blood sampling can significantly reduce unqualified rate of the blood test. ALT is the main reason for the scrapped blood. In addition, HIV infection rate shows an increasing trend in our city. So the development of fixed blood donors and collecting blood from low - risk population is the basic strategy to ensure blood safety.
出处
《徐州医学院学报》
CAS
2012年第11期761-764,共4页
Acta Academiae Medicinae Xuzhou
关键词
无偿献血者
传染性标志物
检测
unpaid blood donors
infectious marker
detection
