摘要
目的探讨泵注东莨菪碱对ARDS患者机械通气时间的影响。方法选择40例严重创伤ARDS患者实施机械通气,20例患者作为治疗组给予持续泵注东莨菪碱,对照组20例为未泵注东莨菪碱患者。治疗中监测生命体征及血气分析、胸部X片、临床症状,同时记录机械通气时间及ICU监护时间,研究对比两组机械通气时间长短,综合评价其疗效。结果治疗后治疗组患者生命体征有明显改善。治疗12h后治疗组的FaO2、氧合指数明显高于对照组(P<0.01),泵注东莨菪碱治疗能够减少机械通气时间及ICU监护时间,与未使用东莨菪碱治疗组相比较,具有统计学意义(P<0.05)。结论泵注东莨菪碱能明显减少严重创伤ARDS患者机械通气时间,可以提高严重创伤ARDS病人的抢救成功率。
Objective To estimate the affect of scopolamine pump infusion to shorten duration of mechanical venti- lation in patients with ARDS. Methods 20 cases of clinical data with severe trauma ARDS patients with mechanical ven- tilation were randomly divided into treatment group treated with continuous infusion of scopolamine and control group not treated with it. The vital signs and blood gas analysis, chest X-films and symptoms were observed. The time of mechani- cal ventilation and ICU monitoring were recorded. Results After treatment, the vital signs improved. The FaO2 and ox- ygenation index in the treatment group after 12h treatment were significantly higher than that in control group （P（ 0.01）. Scopolamine pump infusion treatment could reduce the duration of mechanical ventilation and ICU monitoring time. Conclusion Scopolamine pump infusion can significantly reduce mechanical ventilation in patients with ARDS, and it can improve the survival rate.
出处
《西部医学》
2012年第11期2183-2185,共3页
Medical Journal of West China
关键词
东莨菪碱
成人呼吸窘迫综合征
机械通气
泵注
Scopolamine
Adult respiratory distress syndrome
Mechanical ventilation
Pump infusion
