期刊文献+

药物变态反应的机制 被引量:11

Studies on the mechanism of drug allergies
在线阅读 下载PDF
导出
摘要 目的为了更加清楚的认识日益突出的药物变态反应问题。方法归纳并总结了迄今为止药物变态反应发生的机制研究。结果与结论基于药物变态反应类型与诱发因素的多样性,提示系统研究药物变态反应作用机制的重要性。 Objective To analyze the prominent problems about drug allergies. Methods The studing results, so far, of the mechanism of action in drug allergies were summarized. Results There is diverse in responsive typies and inducing factors of drug allergies. Conclusion It is important for the mechanism of drug allergies to be systimatically investigated.
作者 耿东升
出处 《西北药学杂志》 CAS 2012年第4期385-389,共5页 Northwest Pharmaceutical Journal
关键词 药物变态反应 变态反应类型 作用机制 影响因素 drug allergy allergy type mechanism of action effective factors
  • 相关文献

参考文献27

  • 1耿东升.对药品不良反应定义及其分类的商榷[J].西北药学杂志,2011,26(1):59-61. 被引量:7
  • 2Schnyder B, Pichler W J. Mechanisms of drug-induced allergy[J].Mayo Clin Proc,2009,84(3)-268-272.
  • 3卢建 余应年 徐仁宝.受体信号转导系统与疾病[M].济南:山东科学技术出版社,2001.628-630.
  • 4Lee J H,Kim J W,Ko N Y,et al. Mast cell-mediated al- lergic response is suppressed by Sophorae Flos: inhibi- tion of src-family kinase[J].Exp Biol Med, 2008,233: 1271-1279.
  • 5Hong M H,Kim J H,Na S H,et al. Inhibitory effects of paeonia suffruticosa on allergic reactions by inhibiting the NF-kappa B/I kappa B-alpha signaling pathway and phosphorylation of ERK in an animal model and human mast eells[J].Biosci Bioteehnol Biochem, 2010,74 (6) : 1152-1156.
  • 6耿东升.NF-κB及其致炎作用和化学抑制剂[J].解放军药学学报,2009,25(3):250-253. 被引量:6
  • 7Sakai S, Sugawara T, Matsubara K, et al. Inhibitory effect of carotenoids on the degranulation of mast cells via suppression of antigen-induced aggregation of high affinity IgE receptors[J]. J Biol Chem, 2009,284 (41)- 28172-28179.
  • 8Yoshihiro Suzuki, Chisei Ra. Analysis of the mechanism for the development of allergic skin inflammation and the application for its treatment: aspirin modulation of IgE-dependent mast cell activation: role of aspirin-in- duced exacerbation of immediate allergy[J].J Pharmacol Sci, 2009,110 : 237-244.
  • 9王凤学,周锦,陈新华.围手术期类过敏反应及其防治[EB/OL].[2009-07-16].http:∥biyelunwen.yjbjs.com/fanwen/linchuangyixue/56363.html.
  • 10Torres MJ, Mayorga C, Cornejo-Garcia JA, et al. Moni- toring non-immediate allergic reactions to iodine contrast media[J]. Clin Exper Immunol, 2008,152 : 233-238.

二级参考文献33

共引文献21

同被引文献111

引证文献11

二级引证文献48

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部