期刊文献+

大豆异黄酮的生物学作用及其临床应用的研究进展 被引量:3

Research Progress of Biological Effects and Clinical Applications of Soy Isoflavones
在线阅读 下载PDF
导出
摘要 大豆异黄酮(SIF)是一种天然的雌激素,是大豆生长过程中形成的次级代谢产物,自然界中主要以游离型的糖苷配基和结合型的糖苷两种形式存在,且具有多种的生物学作用及临床应用。主要包括:抗动脉粥样硬化、抗肿瘤、预防骨质疏松、神经保护和抗神经退变的作用、抗菌消炎、提高免疫力的作用、防辐射及雌激素样作用。随着对SIF研究的逐渐深入并日趋成熟,SIF的应用将会越来越广泛。 Soy isoflavone(SIF)is a kind of natural estrogen,a secondary metabolite produced during the process of soybean growth.It mainly exists in two forms in nature,a free glycosidic ligand and the combined one,and has a variety of biological effects and clinical applications,including anti-atherosclerosis,anti-tumor,preventing osteoporosis,neuroprotective and anti-nerve degeneration,anti-bacteria and anti-inflammatory,improving immunity,resisting radiation and estrogen-like effects.With the study of SIF gradually deepening and maturing,the applications of SIF will be more and more extensive.
出处 《医学综述》 2012年第13期2099-2102,共4页 Medical Recapitulate
基金 黑龙江省教育厅科学技术研究项目(11531159)
关键词 大豆异黄酮 生物学作用 临床应用 Soy isoflavones Biological effect Clinical application
  • 相关文献

参考文献30

二级参考文献227

共引文献182

同被引文献53

  • 1刘小旭,康华峰,王西京,代志军,薛锋杰,薛兴欢.环氧化酶-2抑制剂预防大鼠化学性乳腺癌[J].第四军医大学学报,2007,28(1):27-29. 被引量:4
  • 2毛光明,陈江,夏勇,华炜,鹿伟.大豆异黄酮对大鼠脂质的影响及减肥作用研究[J].浙江预防医学,2007,19(7):10-11. 被引量:9
  • 3GANRY O. Phytoestrogen and breast cancer prevention[J].Eur Cancer Prev,2002,(06):519-522.
  • 4JI S,WILLIS G M,FRANK G R. Soybean isoflavoens,genistein and genistin,inhibit rat myoblastproliferation,fusion and myotube protein synthesis[J].Nutrition(Burbank,Los Angeles County,Calif),1999,(07):1291.
  • 5OKI T,SOWA Y,HIROSE T. Genistein induces Gadd45 gene and G2/M cell cycle arrest in the DU145 human prostate cancer cell line[J].FEBS Letters,2004,(01):55-59.
  • 6RAVINDRANATH M H,MUTHUGOUNDER S,PRESSER N. Anticancer therapeutic potential of soy isoflavone,genistein[J].Advances in Experimental Medicine and Biology,2004.121-165.
  • 7REICHLE A,BROSS K,VOGT T. Pioglitazone and rofecoxib combined with angiostatically scheduled trofosfamide in the treatment of far-advanced menlanoma and soft tissue sarcoma[J].Cancer,2004.2247-2256.
  • 8JEMAL A,SIEGEL R,WARD E. Cancer statistics,2007[J].CA:A Cancer Journal for Clinicians,2007,(01):43-46.
  • 9COTTERCHIO M,BOUCHER B A,MANNO M. Dietary phytoestrogen intake is associated with reduced colorectal cancer risk[J].Journal of Nutrition,2006,(12):3046-3053.
  • 10HIROSE K,IMAEDA N,TOKUDOME Y. Soybean products and reduction of breast cancer risk:a case-control study in Japan[J].British Journal of Cancer,2005,(03):15-22.

引证文献3

二级引证文献2

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部