摘要
目的对当前发表的系统评价再评价(overviews of reviews,简称Overviews)纳入研究的质量评价方法进行调查分析,为Overviews制作者提供方法学参考。方法计算机检索Cochrane Library(2010年第1期)、PubMed、EMbase和中国生物医学文献数据库(CBM),检索时间截至2009年12月,遴选出具代表性的Overviews。然后提取其质量评价标准等相关资料进行分析,并对主要质量评价标准进行讨论分析。结果共遴选出43个具有代表性的Overviews,其中32个(74.4%)对纳入的系统评价进行了方法学质量评估,15个采用OQAQ标准(34.9%)、3个采用AMSTAR标准(7.0%)、2个采用DARE清单(4.6%)、2个采用Assendel标准(4.6%)、1个采用E ective Public Health Practice Project标准(2.3%)、6个采用自定义标准(14.0%),1个采用综合标准(2.3%),2个为其他(4.6%)。有10个研究(23.6%)进行了证据质量评价,其中8个研究(18.6%)应用GRADE分级系统进行评价,7个研究(16.3%)同时应用了证据质量评价和GRADE分级评价方法。结论现有Overviews对纳入研究的质量评价包括方法学质量和证据质量,但大多数现已发表的Overviews文献的质量评价实施并不完整。同时,现已发表Overviews中采用的方法学质量评价标准众多,尚无统一标准。鉴于OQAQ标准和AMSTAR标准评价内容全面,实施简易,其应用相对广泛,并得到了推荐,建议Overviews作者合理选择应用。GRADE系统相比其他证据质量分级系统更具系统性和全面性,推荐制作者在研究过程中正确使用,使Overviews研究结果更加完整,便于临床推广应用。
Objective To survey and analyze the quality assessment of the included studies in the Overviews of reviews（Overviews）,so as to provide methodology references for Overviews authors.Methods A computerized search was performed for collecting Overviews in The Cochrane Library（Issue 1,2010）,PubMed,EMBASE,and CBM,and the search time ended by December,2009.Then the relevant data,such as assessment standard etc,were extracted,and the staple standards were analyzed.Results A total of 43 typical Overviews were included.Thirty-two（74.4%） of them assessed the methodology quality of the included systematic reviews with different standards,including OQAQ（34.9%/15）,AMSTAR（9.1%/3）,Checklist from DARE（4.6%/2）,Assendelft scale（4.6%/2）,Effective Public Health Practice Project standards（2.3%/1）,self-formulated standards（14.0%/ 6）,syntaxic standards（2.3%/1）,and other standards（4.6%/2）.Ten Overviews（23.6%） assessed the quality of evidence,including eight（18.6%） applied the GRADE system.Only 7 studies（16.3%） assessed the quality of evidence and applied the GRADE system as well.Conclusion The quality assessment in Overviews includes the assessment of both methodological quality and evidence quality.But most Overviews do not assess comprehensively.The methodological quality standards applied in current Overviews are numerous and no standard is acknowledged.Yet,the OQAQ and AMSTAR are applied widely and recommended because they are comprehensive and easy to be conducted.It suggests that Overviews authors should choose appropriate methodological quality assessment standards according to concrete conditions.The GRADE system is much more comprehensive and systematic than other systems,so it is recommended that Overviews authors should apply GRADE to assess the quality of evidence in their studies in order to make the study results more comprehensive and easier for clinical application.
出处
《中国循证医学杂志》
CSCD
2012年第2期238-242,共5页
Chinese Journal of Evidence-based Medicine
基金
兰州大学中央高校基本科研业务费专项资金资助(编号:lzujbky-2009-t12
lzujbky-2010-183)
兰州大学2010教学研究项目(编号:201022)
关键词
系统评价再评价
系统评价
质量评价方法
Overview of reviews
Systematic review
Quality assessment method
