摘要
目的研究盆炎净片的最佳提取工艺。方法以水提取干浸膏得率和芍药苷为测定指标,采用正交试验方法确定最佳提取工艺。结果最佳提取工艺为12倍量水煎煮2次,每次3.0 h。加水倍数、提取时间对干浸膏得率和芍药苷含量的影响没有显著性差异,提取次数对干浸膏得率和芍药苷含量的影响有显著性差异(P<0.05)。结论确定的制剂工艺和质量控制指标,可以有效保证制剂质量。
Objective To study the best production technology of Penyanjing Pian. Methods To decide the best production technology by the orthogonal experiment design with water extract of dry extract yield and peoniflorin of Paeoniae Rubra Radix as index. Results The best production technology was decocting with 12 times amount of water for 2 times, each time 3 h. The water addition and the extraction time had no significant effect on dry extract yield and content of peoniflorin ,but the extraction frequency influences significantly （P 〈 0.05）. Conclusion This method can not only satisfy extraction process requirements, but also extract the water- soluble effective components fully, meanwhile comfirmed the technical parameters and quality control indicators, can effectively ensure pharmaceutical quality and curative effect.
出处
《现代中药研究与实践》
CAS
2011年第3期59-61,共3页
Research and Practice on Chinese Medicines
关键词
盆炎净片
正交设计
生产工艺
芍药苷
Penyanjing Pian
orthogonal design
production technology
