摘要
[目的]了解甲型H1N1流感病毒裂解疫苗接种后疑似预防接种异常反应（AEFI）发生情况,为制定相关策略提供依据。[方法]2009年10月至2010年4月,平湖市在大规模开展接种工作的同时,开展了甲流疫苗的安全性监测工作。[结果]接种40 744人,报告AEFI发生25例,报告发生率为61.35/10万。报告发生率,一般反应为36.81/10万,异常反应为9.81/10万,偶合反应为7.36/10万,心因反应为7.36/10万。AEFI发生率,女性为96.58/10万,男性为21.05/10万;15-20岁为61.39/10万,20-50岁为59.05/10万,≥60岁为78.98/10万;学生为61.39/10万,医务人员为78.86/10万,教师为83.33/10万,其他职业为52.01/10万。AEFI在接种后10 min至24 h出现,临床表现以低热、局部红肿、疼痛为主,病例均治愈。[结论]接种甲型H1N1流感病毒裂解疫苗AEFI发生率较低。
[Objective]To observe the reaction of Adverse Events Following Immunization（AEFI） of H1N1 flu virus cleavage vaccine,so as to provide basis for relevant strategies.[Methods]During October 2009 to April 2010,a large-scale vaccination of H1N1 flu virus cleavage vaccine was conducted in Pinghu city,as well as safety monitoring for all vaccinated.[Results]A total of 40 744 people received vaccination,there were 25 cases of AEFI,and the incidence was 61.35/105,the incidence of the general reaction was 36.81/105,that of the abnormal reaction was 9.81/105,that of the coupling other diseases reaction was 7.36/105,that of the psychological reaction was 7.36 /105;The incidence in women was 96.58/105,and 21.05/105 in men;The incidence was 61.39/105 in 15 to 20 years old,and 59.05/105 in 21 to 50 years old,and 78.98 /105 in over 60 years old;The incidence was 61.39 /105 in students,and 78.86/105 in medical workers,and 83.33/105 in teachers,and 52.01/105 in other professional;25 cases had clinical symptoms,such as fever,local swelling,and pain,within 10 min to 24h after vaccination,and all were cured.[Conclusion]The AEFI reaction of H1N1 flu virus cleavage vaccine is low.
出处
《预防医学论坛》
2011年第4期373-374,共2页
Preventive Medicine Tribune
