期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

不同剂量瑞芬太尼对老年患者丙泊酚注射痛缓解作用及对血流动力学影响 被引量：18

原文传递
导出
摘要 目的:观察不同剂量瑞芬太尼缓解老年患者丙泊酚注射痛的效果及对患者血流动力学的影响。方法:年龄≥65岁,ASAⅠ～Ⅱ,择期全身麻醉下行手术治疗患者60例随机分为2组各30例,应用瑞芬太尼2ng/mL组(R2组),应用瑞芬太尼4ng/mL组(R4组)。2组均预先静脉靶控注射瑞芬太尼,达到设定血药浓度后,靶控注射丙泊酚。观察患者疼痛分级及不适反应,记录用药前、插管前、插管后1,3,5min血压、心率并进行比较。结果:R2组丙泊酚注射后疼痛发生率高于R4组(P<0.05);R2组插管前、插管后3,5min收缩压、舒张压、心率、平均动脉压与用药前比较差异均有统计学意义(P<0.05);R4组插管后1min心率与用药前比较差异无统计学意义(P>0.05),余指标插管前、插管后1,3,5min与用药前比较差异均有统计学意义(P<0.05);R4组插管前,插管后1,3min收缩压低于R2组(P<0.05),插管后1min舒张压、平均动脉压低于R2组(P<0.05)。结论:4ng/mL瑞芬太尼缓解丙泊酚注射痛优于2ng/mL瑞芬太尼,2种剂量均可引起血压下降及心率减慢。
作者 严蓉 郭松青
机构地区 苏北人民医院麻醉科
出处 《中华实用诊断与治疗杂志》 2011年第2期184-185,共2页 Journal of Chinese Practical Diagnosis and Therapy
关键词 瑞芬太尼 丙泊酚 注射痛 血流动力学
分类号 R614 [医药卫生—麻醉学]
  • 相关文献

参考文献11

  • 1Tan C H. Onsing M K. Pain on injection of propofol[J].Anesthesia,1998,53(5) :468 -476.
  • 2Pieard P, Tramer M R. Prevention of pain on injection with propofol: a quantitative systematic revtew[J]. Anesth Analg,2000,90(4):963 -969.
  • 3Miller R D. Miller's anesthesia[M]. 7th ed. Philadelphia: Churchill I.ivingstone, 2010 : 2261- 2976.
  • 4Ambesh S P, Dubey P K, Sinha P K. Ondasetron pretreatment to alleviate pain on propofol injection: a randomized, controlled, double-blinded study[J]. Anesth Analg, 1999,89 ( 1 ) : 197-199.
  • 5Iwama H, Nakane M, Ohmori S. etal. Nafamostat mesilate, a kallikrein inhibitor, prevents pain on injection with propofol[J]. Br J Anaesth, 1998,81 (6) :934-964.
  • 6高梅,钱燕宁,张人胜.5.0%碳酸氢钠和2.5%硫喷妥钠对139例患者丙泊酚注射痛的疗效分析[J].南京医科大学学报（自然科学版）,2004,24(6):647-649. 被引量：7
  • 7Koo S W, Cho S J, Kim Y K, et al. Small-dose ketamine reduces the pain of propofol injection[J].Anesth Analg,2006, 103(6) :1444- 1447.
  • 8Albertin A, Casati A, Federica I., et al. The effect-site concentration of remifentanil blunting cardiovascular responses to tracheal intubation and skin incision during bispectral index guided propofol anesthesia[J].Anesth Analg, 2005,101 ( 1 ) : 125-130.
  • 9Kwak K, Kim J, Park S, et al. Reduction of pain on injection of propofol; combination of pretreatment of remifentanil and premixture of lidocaine with propofol[J].Eur J Anaesthesiol, 2007,24 (9) : 746-750.
  • 10许川雅,吴新民,蒋建渝.老年患者靶控输注瑞芬太尼和丙泊酚的临床评价[J].北京大学学报（医学版）,2005,37(5):513-515. 被引量：23

二级参考文献17

  • 1[1]King SY, Davis FM, Wells JE, et al. Lidocaine for the prevention of pain due to injection of propofol[J]. Anesth Analg, 1992, 74: 246-249.
  • 2[2]Kau YC, Wu RS, Cheng KS. Propofol-sodium thiopental admixture reduces pain on injection [J]. Acta Anaesthesiol, 2000, 38: 9-13.
  • 3[3]Ambesh SP, Dubey PK, Sinha PK. Ondansetron pretreatment to alleviate pain on propofol injection: a randomized, controlled, double-blinded study [J]. Anesth Analg, 1999, 89: 197-199.
  • 4[4]Memi D, Turan A, Karamanliolu B, et al. The prevention of propofol injection pain by tramadol or ondansetron[J].Eur J Anaesthesiol, 2000, 19: 47-51.
  • 5[5]Huang YW, Buerkle H, Pryor PJ, et al. Effect of pretreatment with ketorolac on propofol injection pain[J].Acta Anaesthesiol Scand, 2002, 46: 1021-1024.
  • 6[6]Dilek M, Alparslan T, Beyhan K, et al. The use of magnesium sulfate to prevent pain on injection of propofol[J]. Anesth Analg, 2002, 95: 606--608.
  • 7[7]Macario A, Weinger M,Truong P, et al. Which clinical anesthesia outcomes are both common and important to avoid? The perspective of a panel of expert anesthesiologists[J]. Anesth Analg, 1999, 88: 1085-1091.
  • 8[8]Iwama H, Nakane M, Ohmori S Daneko T, et al.Nafamostat mesilate, a kallikrein inhibitor, prevents pain on injection with propofol [J]. Br J anaesth, 1998, 81:963-964.
  • 9Johannsen EK, Manro AJ. Remifentanil in emergency caesarean section in pre-eclampsia complicated by thrombocytopenia and abnormal liver function[J]. Anesth Intensive Care, 1999, 27: 527-529
  • 10Servin FS. Remifentanil: an update[J]. Curr Opin Anaesthesiol, 2003, 16: 367-372

共引文献28

同被引文献190

引证文献18

二级引证文献124

中华实用诊断与治疗杂志
2011年 第2期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部