摘要
用正交设计法研究了离子缔合物的种类、膜相中活性物浓度和增塑剂3个因素对电极性能的影响,以四苯硼-洛美沙星形成的缔合物为电活性物质研制了涂碳PVC膜洛美沙星电极.其能斯特响应范围为2.0×10^(-3)～1.0×10^(-5)mol/L;检测限为4.0×10^(-6)mol/L,级差为28.9mV/pC.该电极响应迅速,重复性和稳定性好,应用于洛美沙星药片的含量测定,方法简便,结果满意.
The influences of various electroactive materials, concentration of activator in membrane phase and plasticizier on the properties of electrode have been studied by orthogonal design. A carbon rod electrode coated with polyvinyl chloride were prepared by using tetraphenylboron-lomefloxacin aselectroactive material. The Nemstian range of the electrode was from 2.0×10-3 to 1.0×10-5 mol/L,the detection limit was 4.0×10-6 mol/L and the electrode slope was 28. 9mV/pC. The electrodeexhibited characteristics of fast response, good reproducibility and stability. It has been used to determine the lomefloxacin in tablets with satisfactory results.
出处
《分析化学》
SCIE
EI
CAS
CSCD
北大核心
1999年第10期1117-1120,共4页
Chinese Journal of Analytical Chemistry
基金
国家自然科学基金资助课题(批准号:29475199)
关键词
洛美沙星
抗菌药
离子选择电极
测定
Lomefloxacin, antibacterial drug, ion selective electrode
