摘要
目的:探讨不同力竭标准判断对负重大鼠游泳运动疲劳程度的影响。方法:成年雄性SD大鼠24只,随机分为对照组、运动组1、运动组2,每组8只,每天对负重大鼠进行游泳训练,运动组1以大鼠连续反复下沉,沉入水下三次,每次超过五秒为力竭标准,运动组2以沉入水下十秒钟,且游泳失去平衡为评判标准,对照组不参与游泳运动,试验期为十天,记录游泳时间,末了处死大鼠,取血液、肝、骨骼肌,同时检测相应组织超氧化物歧化酶活性,乳酸、丙二醛的含量。最后进行统计比较和分析。结果:运动组1随着游泳天数的增加,游泳时间呈逐渐延长趋势,运动组2游泳随着游泳天数的增加,游泳时间呈缩短趋势。运动组1和对照组相比较,血清、骨骼肌丙二醛和乳酸明显高(P<0.05),肝变化不明显(P>0.05);超氧化物歧化酶的活性均明显降低(P<0.05)。运动组2和对照组、运动组1相比较,血清、骨骼肌丙二醛和乳酸明显高(P<0.05),肝变化不明显(P>0.05);超氧化物歧化酶的活性均明显降低(P<0.05)。结论:采用运动组2疲劳力竭判断标准是可靠的,可用于运动性疲劳机制的试验性研究。
Objective：To investigate the effect of the rat＇s fatigued extent on the heavy-loaded swimming training by the different standard of swimming to exhausition.Methods：24 male SD rats were randomly divided to 3 groups（8 rats in each group） ：control group, first group and econd group.The last two groups were subjected to 10 days loaded-swimming training exercise.The control group was not subjected to exercise.The first standard of swimming to exhausition was that the rats were flooded 3 times in series and 5 seconds every time.The second standard of swimming to exhausition was that the rats were flooded 10 seconds and swimming in disorder.The swimming time was recorded and the contents of lactic acid, malondialdehyde （MDA）, hemocuprein （SOD） in the liver, skeletal muscle and blood serum were detected.Results：The swimming time of the first group was gradually extended with training exercise while the second group was opposite; The levels of lactic acid and MDA in blood serum and skeletal muscle except the liver in first group were significantly higher than that in the control group （P0.05） while the activities of SOD were significantly lower than that in the control group （P0.05）.The levels of lactic acid and MDA in blood serum and skeletal muscle except the liverin the second group were significantly higher than that in the control group and the first group （P0.05） while the activities of SOD were significantly lower compared with the control group and the first group （P0.05）.Conclusions：The standard of the second group is reliable and can be used in the ex-periment research of sports fatigue mechanism.
出处
《现代生物医学进展》
CAS
2010年第15期2855-2858,共4页
Progress in Modern Biomedicine
基金
学校军事医学重大项目之分题(08XJZOO4)
关键词
大鼠
疲劳
力竭标准
游泳
Rat
Fatigue
Standard of exhausition
Swimming
