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^(99)Tc^m-MDP骨显像对乳腺癌骨转移特征的评价分析 被引量:5

Evaluation of bone metastasis characteristics of primary breast cancer with ^(99)Tc^m-MDP whole body bone imaging
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摘要 目的:探讨原发性乳腺癌患者骨骼转移病灶的影像特征。方法:对212例病理确诊的乳腺癌患者行全身骨骼显像,分析各骨骼骨转移率、病灶构成及病灶形态特征。结果:患者骨转移率41.5%(88/212),中轴骨骨转移率38.7%(82/212),四肢骨20.3%(43/212),中轴躯干骨38.7%(82/212),四肢带骨18.4%(39/212),肋骨、胸椎、腰椎、髂骨、胸骨骨转移率较高。身体左右两侧病灶数目差异无统计学意义,χ2=0.356,P=0.551。骨转移病灶形态:点状72.9%(495/679),团状14.7%(100/679),条状7.5%(51/679),片状4.9%(33/679)。浓聚病灶98.7%(760/770),混合性病灶0.5%(4/770),稀疏病灶0.8%(6/770)。结论:乳腺癌易发生骨转移,骨转移好发于中轴躯干骨和四肢带骨。早发病灶分布无明确规律,晚期骨转移病灶随机性广泛分布,并且常呈多发性多形态病灶并存的特征。 OBJECTIVE: To explore the image characteristics of bone metastasis of primary breast carcinoma.METHODS: The whole body bone imaging was performed for 212 patients with breast carcinoma proved by pathology.The rate of bone metastasis,metastatic lesion distribution,and their form were analyzed.RESULTS: The total rate of bone metastasis was 41.5%(88/212),the rate of axial skeleton was 38.7%(82/212),appendicular skeleton 20.3%(43/212),the trunk bone of center axis 38.7%(82/212),and appendicular gridle skeleton 18.4%(39/212),and that of rib,thoracic vertebra,lumbar vertebra,ilium and breast bone was more than that of other bones.It was not significantly different for the number of matastic lesions of bone between left side and right side(χ2=0.356,P=0.551).The metastatic lesions of bone consisted of 72.9%(495/679) of point form,14.7%(100/679) of lump form,7.5%(51/679) of strip form and 4.9%(33/679) of lamellar form.Totally 98.7%(760/770)of metastatic lesion were strong radioaction,0.5%(4/770)of those were mingled,and 0.8%(6/770) of those were low radioaction.CONCLUSIONS: The bone metastasis is very common in the patients with breast cancer.The bone metastasis,which is mostly characterized by strong radioaction and earlier point form,often exists in the trunk bone of axial skeleton or appendicular gridle skeleton.The distribution of earlier metastasis has not positive regularity,and that of advanced stage,which is often characterized by concurrent multilesion and multiform,is wide and random.
作者 汪长银
出处 《中华肿瘤防治杂志》 CAS 2010年第13期1015-1017,共3页 Chinese Journal of Cancer Prevention and Treatment
关键词 乳腺肿瘤 肿瘤转移 骨显像 breast neoplasms neoplasm metastasis bone scan
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