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乳腺癌骨转移和骨相关疾病临床诊疗专家共识(2008版) 被引量:35

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摘要 乳腺癌骨转移在复发转移乳腺癌中的发生率为65%~75%。乳腺癌远处转移中,首发症状为骨转移者占27%~50%。骨痛、骨损伤、骨相关事件(skeletal related event.SRE)的发生及生活质量的降低是乳腺癌骨转移的常见并发症。SRE是指在临床试验中表明双膦酸盐类药物治疗失败的研究观察终点,一般定义为骨痛加剧或出现新的骨痛、病理性骨折、椎体压缩或变形、脊髓压迫、骨放疗、骨转移病灶进展及高钙血症等事件,是影响患者自主活动能力和生活质量的主要因素。
出处 《中华肿瘤杂志》 CAS CSCD 北大核心 2009年第2期156-159,共4页 Chinese Journal of Oncology
关键词 乳腺肿瘤 骨肿瘤 肿瘤转移 Breast neoplasms Bone neoplasms Neoplasm metastasis
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参考文献10

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