摘要
目的探讨重型乙型肝炎患者血小板参数变化与病情的关系。方法应用电子阻抗法检测７０例重型乙型肝炎患者和１２９例健康者血浆ＰＬＴ及ＭＰＶ。结果患者组ＰＬＴ减少率为７５７％，与健康对照组比较差别有极显著性意义（Ｐ＜０．０１）。患者ＰＬＴ减少，则ＭＰＶ变大（Ｐ＜００１）；患者ＰＬＴ正常，则其ＭＰＶ与健康对照组的差别无显著性意义（Ｐ＞００５）。病情好转组ＰＬＴ比死亡组ＰＬＴ高（Ｐ＜００５）。结论患者ＰＬＴ的变化与疾病预后有一定关系，ＰＬＴ增加，预后良好。且患者ＰＬＴ减少与乙肝病毒感染体内免疫作用有一定关系。
Objective\ To study the relationship between the changes of platelet parameters and clinical
manifestation.Methods An electronic impedance method was used for the detection of plasma
PLT and MPV in 70 cases of patients with severe HBV hepatitis and 129 cases of healthy
control subjects.Results\ The percentage of PLT decrease was 75.7% in patient group.The
difference of PLT decrease in patient group was very significant in contrast with that of the
healthy control group ( P <0.01).MPV increased significantly ( P <0 01) in PLT decreased
patients,but no difference was found between MPV in normal PLT patient and that of healting
control group ( P >0.05).PLT in improved patient group was higher than that in death group ( P
<0.05).Conclusion It is suggested that a relationship between the variations of blood platelet
parameters and the prognosis of patient with HBV hepatitis exists.The prognosis became better
in PLT increased patients.And there is also a relationship between PLT decrease and body
immunization of patient infected by HBV.
出处
《中国实用内科杂志》
CAS
CSCD
北大核心
1999年第2期87-88,共2页
Chinese Journal of Practical Internal Medicine
关键词
乙型肝炎
血小板计数
平均血小板体积
Severe HBV hepatitis\ Blood platelet count\
Mean blood platelet volume
