摘要
目的探讨赛乐特对帕金森病(PD)伴发的抑郁焦虑的治疗效果。方法 42例PD患者随机分成赛乐特加PD常规治疗组(治疗组),及单纯PD常规治疗组(对照组),治疗前后对病情严重程度使用帕金森氏病综合评分量表(UPDRS)、抑郁量表(HAMD)、焦虑量表(HAMA)进行评分。结果治疗组治疗后UPDRS、HAMD、HAMA评分明显降低(P<0.01),而对照组无明显变化,两组相比差异有统计学意义(P<0.01)。结论赛乐特可改善PD患者伴发的抑郁焦虑症状,并有助于改善生活质量。
Objective To study clinical efficacy and safety of Seroxat in the treatment of Parkinson＇s disease（PD） patients with depression and anxiety.Methods 42 PD patients with the symptoms of depression and anxiety were randomly divided into two groups.22 patients in the Seroxat group were treated with Seroxat 20 mg /d,po,qd for six weeks.20 patients in the control group were treated with conventional anti-Parkinson drugs without Seroxat for the same six weeks period.Result The scores of UPDRS,HAMD and HAMA in the Seroxat group was significantly lower than the control group（P0.01）.Conclusion Seroxat may relieve the PD associated depression and anxiety symptoms.
出处
《热带医学杂志》
CAS
2010年第6期686-687,共2页
Journal of Tropical Medicine
关键词
帕金森病
抑郁焦虑
赛乐特
Parkinson＇s disease
depression and anxiety
Seroxat
