摘要
目的探讨多层螺旋CT(MSCT)灌注扫描成像技术在评价肝脏泡状棘球蚴病边缘区域血流状态的临床应用价值。方法 24例肝脏泡状棘球蚴病患者均行肝脏MSCT灌注扫描检查,获得病灶中心、边缘区域及周围肝脏组织的各项灌注参数,包括血流量(BF)、血容量(BV)、平均通过时间(MTT)、毛细血管表面通透性(PS)、肝动脉灌流分数(HAF)、肝动脉灌流量(HAP)、门静脉灌流量(PVP),进行统计学分析。结果 24例中,肝脏泡状棘球蚴病灶中心、边缘区域及周围肝脏组织的各项灌注参数BF、BV、MTT、PS、HAF、HAP、PVP的均值差异有统计学意义(P<0.01)。边缘区域组与周围肝脏组织组BF、MTT、PS、HAP、PVP参数间差异有统计学意义(P<0.05),BV和HAF参数间差异无统计学意义(P>0.05)。结论肝泡状棘球蚴病灶与周围肝组织间存在边缘浸润带,该区域血流灌注高于病灶内部及周围肝脏组织,CT灌注成像可以反映这一区域的血流状态及病灶的浸润范围,具有一定的临床应用价值。
Objective To investigate the clinical value using of multi-slice spiral CT（MSCT） perfusion technology in evaluating the hemodynamic changes of peripheral zone of Hepatic Alveolar Echinococcosis（HAE）.Methods Twenty four cases with HAE underwent GE 64-slice spiral CT perfusion.The perfusion parameters of the center,the peripheral zone of focus and the around liver tissue of lesion were measured and statistically analyzed,which including blood flow（BF）,blood volume（BV）,mean transit time（MTT）,permeability surface area product（PS）,hepatic arterial fraction（HAF）,hepatic arterial perfusion（HAP）,portal vein perfusion（PVP）,respectively.Results There was statistically significant difference in BF,BV,MTT,PS,HAF,HAP and PVP among the groups of the center,the peripheral zone and the around liver tissue of lesion of 24 cases.The BF,MTT,PS,HAP and PVP between the groups of the peripheral zone of lesion and the around liver tissue of lesion were statistically significant（P0.05）.However,the BV and HAF between the two groups were not statistically significant（P0.05）.Conclusion The blood supply of peripheral zone of HAE is much more than that in the center of the lesion and around liver tissue.CT perfusion technique is of clinical significance in analyzing the change of the blood flow of peripheral zone and invasive extent of HAE.
出处
《新疆医科大学学报》
CAS
2010年第4期375-378,共4页
Journal of Xinjiang Medical University
基金
新疆维吾尔自治区重点实验室开放课题(XJDX0202-2007-03)
