摘要
目的:探讨18F-FDG符合线路SPECT/CT显像对于胃癌诊断和转移灶探查及治疗后随访的价值。方法:60例疑似胃癌患者行18F-FDG符合线路SPECT/CT显像,以术后病理结果作为金标准,对18F-FDG符合线路SPECT/CT显像用于原发灶及转移灶诊断的灵敏性、特异性、准确性进行分析,并用于30例胃癌患者治疗后随访。图像分析采用视觉及T/N值(靶与非靶比值)。结果:对胃癌原发病灶的定性诊断,灵敏性为80.8%,特异性为90%,准确性为81.7%;30例证实有转移的患者中,局部淋巴结转移20例,12例18F-FDG符合线路SPECT/CT显像为阳性,灵敏性为60%(12/20);对肿瘤远处组织或器官转移的检出,10例中8例为阳性,灵敏性为80%(8/10)。30例胃癌治疗后随访患者,对于复发及转移灶的检测,18F-FDG符合线路SPECT/CT显像灵敏性为90%(18/20),特异性为100%(10/10)。结论:18F-FDG符合线路SPECT/CT显像对胃癌诊断的灵敏性高,特异性好;对局部及远处转移的探查有很好的价值,可为临床分期和制定治疗方案提供有益的参考;亦可以用于治疗后随访,早期发现复发和转移灶。
Objective To explore the value of the 18F-FDG coincidence SPECT /CT in diagnosis of gastric carcinoma,explore metastasis,and in post-treatment follow-up visit.Method 60 cases of suspect gastric carcinoma patients were evaluated by the 18F-FDG coincidence SPECT /CT,with the post-operation pathologic result as the golden standard,in order to analyze the sensitivity,specificity,and accuracy of the 18F-FDG coincidence SPECT /CT in diagnosing primary lesion and metastasis,and in post-treatment follow-up visit.The image analysis was adapted to vision and targeted to non-target ratio value.Results In the qualitative diagnosis of the primary lesion of gastric carcinoma the sensitivity,specificity and accuracy were 80.8%,90% and 81.7% respectively.In 30 cases confirmed to have metastasis,20 of them have partial nodular transfer.Among them 12 cases detected by 18F-FDG coincidence SPECT /CT shown positive,which gave the sensitivity of 60%（12 /20）;Among the 10 cases with tumor metastasis,8 cases were positive which the sensitivity was 80%（8 /10）.30 cases of stomach carcinoma post-treatment follow-up visit were detected for recrudescence and metastasis by 18F-FDG coincidence SPECT /CT,the sensitivity was 90%（18 /20）,the specificity was 100%（10 /10）.Conclusion The sensitivity and specificity of the 18F-FDG coincidence SPECT /CT in diagnosis of gastric carcinoma are both high,which is valuable for the detection of regional and distant metastasis,and is benefit for clinical staging and therapeutic regimen selection,as well as to detect early recrudescence and metastasis in post-treatment followup visit.
出处
《实用医学杂志》
CAS
北大核心
2009年第22期3796-3798,共3页
The Journal of Practical Medicine
