摘要
目的:了解我院严重药品不良反应(ADR)发生的情况和特点,以促进合理用药。方法:对我院2006年1月～2008年9月收集到的21例严重ADR报告,按ADR因果关系判断标准进行分析、评价。结果:引起ADR例/次最多的是抗感染药,占52.38%;注射剂ADR构成比居首位,占80.95%;过敏性休克比例最高,占28.57%。结论:应加强合理用药意识,慎用注射剂,以减少和避免严重ADR的发生,保证药物治疗安全有效。
Objective： To investigate the situation and characteristics of serious adverse drug reactions（ADR） in our hospital in order to promote the rational clinical drug use. Method： 21 severe ADR cases collected in our hospital from January 2006 to September 2008 were statistically analyzed and evaluated based on the ADR causality judgement criteria. Result： Anti-infectives had the highest proportion to induce ADRs （52. 384% ） , injections occupied the topped incidence rate with 80.95% , and anaphylactic shock reported the highest ADR incidence rate with 28.57%. Conclusion： It is nec- essary to strengthen the awareness of the rational drug use to guard against severe ADRs and ensure the safe and effective medication. Injections should he rationally used under cafcful observation.
出处
《药物流行病学杂志》
CAS
2010年第1期33-35,共3页
Chinese Journal of Pharmacoepidemiology
