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老年患者瑞芬太尼诱导气管插管的静脉输注速率探讨

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摘要 目的探讨老年患者瑞芬太尼诱导气管插管的适合静脉输注速率。方法选择75例行普外科择期手术的老年患者,将所有患者随机分为3组:R-a组、R—b组、R—c组,各25例。3组瑞芬太尼行诱导气管插管时的静脉输注速率分别为0.075μg/(kg·min)、0.125μg/(kg·min)、0.175μg/(kg·min)。结果R—a组的血液动力学指标在气管插管前后波动最为剧烈,SP、DP、HR指标,R—b组与R—c组在大部分时刻都与R—a组差异有统计学意义(P〈0.05),而R—b组相对于R—c组波动更小。R—a组的插管反应发生率(84%)显著高于R—b(28%)和R—c组(16%)。R—c组的副作用发生(80%)率则显著高于R-b组(28%)和R—a组(8%)。结论老年患者瑞芬太尼诱导气管插管的静脉输注速率为0.125μg/(kg·min)时,能够较好地控制血液动力学指标,同时插管反应与副作用的发生率均较低。
出处 《中国医师杂志》 CAS 2009年第10期1429-1430,共2页 Journal of Chinese Physician
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