摘要
目的观察自然夜间多导睡眠图(PSG)对首发抑郁症患者的诊断价值。方法应用日本1518K多导睡眠生理仪,采用眼电图和下颌肌电图及脑电图等技术,对24例首发抑郁症患者的多导睡眠图(PSG)进行整夜监测,并与21名正常受试者对照。结果首发抑郁症患者组PSG主要指标表现为REM睡眠潜伏期(RL)前移[正常组(81±11)min,首发抑郁症患者组(62±19)min,P<0.01];睡眠维持率(SMT)下降[正常组(98±5)%,首发抑郁症患者组(87±8)%,P<0.01],第二阶段睡眠降低[正常组(57±5)%,首发抑郁症患者组(43±12)%,P<0.01]及REM3个睡眠参数有改变。结论REM睡眠潜伏期前移是首发抑郁症的特点。
Objective： To estimate the diagnostic value of . spontaneous evening sleep polysomnography （PSG） in first episode depression. Methods： The whole night PSG were recorded from 24 patients with first episode depression, and 21 normal subjects, using Neurofax - 1518K （Nihon Kohden） sleep instrument. Results： Compared with normal subjects, first episode depression patients showed shorted REM latency （ NC ： 81 ± 11, first episode depression group ： 62 ± 19, P 〈 0.01 ）, reduced sleep maintenance （ NC ： 98 ± 5%, first episode depression group： 87 ± 8% , P 〈 0.01 ） , decreased stage 2 sleep （ NC： 57 ± 5% , first episode depression group： 43 ± 12%, P 〈 0. 01 ）. Conclusion： Patients with first episode depression exhibit abnormality in sleep continuity, sleep frame, and REM.
出处
《上海精神医学》
2009年第2期92-95,共4页
Shanghai Archives of Psychiatry
关键词
首发抑郁症
多导睡眠图
睡眠
快速眼运动
First episode depression Polysomnography Spontaneous sleep Rapid eye movement
