摘要
目的:探讨我院头孢吡肟用量、用药频度和耐药率之间的相关性。方法:采用回顾性分析方法,对2006年1月～2007年12月间临床常见检出菌对头孢吡肟的敏感率及其医院同期该药的使用量、用药频度等进行统计分析。结果:2年中,头孢吡肟的用量在不断增加,常见检出菌对头孢吡肟的耐药率也呈增长趋势,头孢吡肟的用药频度与金黄色葡萄球菌、铜绿假单胞菌耐药率相关系数分别为r=0.624 3、r=0.800 5。结论:用药频度的增高与常见检出菌对该药耐药率的增加有一定的相关性。
Objective：To study the correlation between quantities of cefepime prescribed, Daily de- fined doses （DDDs） and the drug-resistance. Methods： The susceptible rates of clinical pathogens, the consumptions and the DDDs of cefepime from 2006 to 2007 were investigated and analyzed retrospectively by statistics. Results： The resistant rates of clinical pathogens to cefepime increased with quarters. The analysis revealed a correlation between the quality of cefepime and the resistance of Staaur （ r = 0. 624 3） and pseaer （r = 0. 800 5）. Conclusions ： The increase of DDDs had a significant relationship with the addition of resistant rates of clinical pathogens to cefepime.
出处
《药学与临床研究》
2009年第1期61-63,共3页
Pharmaceutical and Clinical Research
