摘要
运用显微激光拉曼仪测定了正常小鼠离体皮肤0-300μm不同深度的拉曼光谱。实验还测定了8 mm辐照一定时间后小鼠受辐照皮肤组织的拉曼光谱。实验结果表明毫米波辐照后皮肤拉曼光谱峰位857,936,1658 cm^-1的相对强度随着辐照时间的增加而减少。这表明由于毫米波热效应皮肤组织中的胶原蛋白构象发生了改变甚至分解,从而进一步表明皮肤组织受到了不可恢复的损伤。
An experimental study on Raman spectroscopy of normal murine skin and the skin irradiated by high power millimeter wave（HPMM） is presented.It is showed that the Raman spectra of normal skin mainly originate from collagen,and the characteristic peaks are 857,936 and 1 658 cm- 1.The result showed that after irradiation by HPMM,the relative intensity of the characteristic peaks at 857 and 936 cm^-1 of Raman spectra was decreased.This meant that the collagen was destroyed and even damaged.It was probably indicated that the skin tissue was damaged and could not be restored.The result also showed that the intensity of the characteristic peak at 1 658 cm^-1 of the skin tissue irradiated by millimeter wave with the duration of 20 s decreased. It was considered that the protein in the skin was destroyed.Those results were consistent with macroscopic observation results.
出处
《光谱学与光谱分析》
SCIE
EI
CAS
CSCD
北大核心
2008年第12期2872-2875,共4页
Spectroscopy and Spectral Analysis
基金
国家"863-803"项目资助
关键词
高功率毫米波
皮肤组织
拉曼光谱
High power millimeter wave
Skin tissues
Raman spectroscopy
