摘要
采用腹腔注射的方法在９０只昆明种小鼠中进行了镉中毒与硒解毒的研究。结果表明，镉中毒组在注射后１～５周内，表现出明显的病理变化，特征为全身小动脉血管及肝、肾、心、肺、脑等器官有严重的病理损伤，且肝脏超微病变明显；而硒解毒组小鼠上述变化明显减轻，以肝、心、脾表现最为明显，结果表明硒可颉颃镉在小鼠的毒性。
An experimental study on the cadmium poisoning and its detoxification by selemium was carried out through intra_peritoneal injection in 90 mice. In 1～5 weeks after treament,some prominent pathologicalchanges,including typical histopathological and ultrastructural lesions occurred in the arteriol,liver,kidney,lung,heart and central nervous system etc. At the end of the experiment however,in the supplemented group with selenium,above_mentinoned lesions were mild.It follow that selenium can simultaneously antagonize the toxicity of cadmium in mice.
出处
《畜牧与兽医》
北大核心
1998年第1期9-10,共2页
Animal Husbandry & Veterinary Medicine
关键词
硒
镉
小鼠
病理损伤
保护效应
selenium
cadmium
mice
pathological lesions
