摘要
目的探讨系统性红斑狼疮(SLE)合并感染患者的临床特点和相关因素。方法回顾性分析352例SLE患者,收集整理其临床和实验室资料,并将有感染患者和无感染患者进行比较。结果352例SLE患者中有158例发生了187例次感染,其中89例为医院感染,29例发生了2种或2种以上的感染,细菌感染最常见,其次是真菌和病毒感染,感染部位以呼吸道最常见,其次为泌尿道。合并感染的SLE患者治疗后,121例好转,20例死亡,未愈者17例。结论SLE患者容易发生感染,且感染是SLE患者主要死亡原因之一。积极采用综合防治措施是降低病死率的关键。
Objective To investigate the clinical features and relevant factors of infection in systemic lupus erythematosus （SLE） patients. Methods Retrospective analysis was carried out on the clinical and laboratory data of 352 patients with SLE and compared between patients complicated with infections and those without infections. Results A total of 187 episodes of in- fection were identified in 352 SLE patients, including 89 cases of nosocomial infection. Two or more infections were identified in 29 cases. Bacteria were the most common pathogen, followed by fungus and virus. Respiratory tract infection was the most common followed by urinary tract infection. After treatment, 121 cases were improved, and 20 cases died, Conclusions The SLE patients are susceptible to infection. Infection is one of the main causes of death in SLE patients. Comprehensive and active control measure is the key for reducing SLE mortality.
出处
《中国感染与化疗杂志》
CAS
2008年第5期362-365,共4页
Chinese Journal of Infection and Chemotherapy
关键词
系统性红斑狼疮
易感因素
感染
Systemic lupus erythematosus
Predisposing factor
Infection
