摘要
为了探讨一氧化氮(NO)在消化性溃疡发病机理中的作用,对38例内镜下所见消化性溃疡活动期与愈合后患者,采用高效液相色谱(HPLC)法,测定了其血浆、胃液及粘膜组织的NO水平。结果:消化性溃疡活动期患者NO水平显著高于愈合后患者(P<0.01),且伴有幽门螺杆菌(HP)感染者NO水平也明显增高,随着HP的根除,NO水平也明显降低。提示:NO可能在消化性溃疡的发病机理中起一定的作用。
In order to study the pathogenicity of nitric oxide (NO) in peptic ulcers (PU). The NO levels in the plasma, gastric juice and gastric mucosa of 38 PU patients with active lesions diagnosed by endoscopy were determined with high performance liquid chromatography ( HPLC). The NO levels of PU in the active stage were significantly higher than those of patients after treatment (P<0.01). The NO levels were also significantly higher in patients with He-licobacter pylori infections, and significantly decreased with H. pylori eradication. The results suggest that NO may play a role in the pathogenesis of PU.
出处
《中国内镜杂志》
CSCD
1997年第1期9-10,共2页
China Journal of Endoscopy
