摘要
我们检测了９００多例男性不育症患者的血清、精浆抗精子抗体（ＡｓＡｂ）和精液各项指标，对其中２１３例ＡｓＡｂ阳性患者的精液有关参数与ＡｓＡｂ的关系进行了分析，并与生育男性组作了比较。结果表明，ＡｓＡｂ阳性患者的精子密度、精子活率、精子顶体完整率、精浆免疫抑制物（ＳＰＩＭ）及α－糖苷酶均明显低于生育组（Ｐ＜０．０１），不育男性ＡｓＡｂ阳性组ＳＰＩＭ阳性率也明显高于ＡｓＡｂ阴性组（Ｐ＜０．０１）。此外，血清与精浆ＡｓＡｂ同为阳性组的精子活率明显低于单纯血清或精浆ＡｓＡｂ阳性组（Ｐ＜０．０１）。
Anti-sperm antibody(AsAb) in serum and seminal plasma and semen parameters were determined in 900 male infertiles. 213 patients of which AsAb was positive were analysed on the relationship between anti-sperm antibody and semen parameters. They were compared with fertile control also. The resultsshowed that the sperm density, sperm viability, percentage of intact sperm acrosome, seminal plasma immunodepressive material and α-glucosidase were all significantly lower than those in the control ( P<0.01). When AsAb was all positive in serum and seminal plasma, sperm viability was significantly lower compared with the one that AsAb was positive either in serum or in seminal plasma ( P<0.01).
关键词
不育症
抗精子抗体
精液参数
Infertility
Anti-sperm antibody
Semen parameters
