期刊文献+

Using computed tomography scans to develop an ex-vivo gastric model

Using computed tomography scans to develop an ex-vivo gastric model
在线阅读 下载PDF
导出
摘要 The objective of this research was to use abdominal computed tomography (CT) scans to non-invasively quantify anthropometrical data of the human stomach and to concomitantly create an anatomically correct and distensible ex-vivo gastric model. Thirty-three abdominal CT scans of human subjects were obtained and were imported into reconstruction software to generate 3D models of the stomachs. Anthropometrical data such as gastric wall thickness, gastric surface area and gastric volume were subsequently quantified. A representative 3D computer model was exported into a selective laser sintering (SLS) rapid prototyping machine to create an anatomically correct solid gastric model. Subsequently, a replica wax template of the SLS model was created. A negative mould was offset around the wax template such that the offset distance was equivalent to that of the gastric wall thickness. A silicone with similar mechanical properties to the human stomach was poured into the offset. The lost wax manufacturing technique was employed to create a hollow distensible stomach model. 3D computer gastric models were generated from the CT scans. A hollow distensible silicone ex-vivo gastric model with similar compliance to that of the human stomach was created. The anthropometrical data indicated that there is no significant relationship between BMI and gastric surface area or gastric volume. There were inter- and intra-group differences between groups with respect to gastric wall thickness. This study demonstrates that abdominal CT scans can be used to both non-invasively determine gastric anthropometrical data as well as create realistic ex-vivo stomach models. The objective of this research was to use abdominal computed tomography (CT) scans to non-invasively quantify anthropometrical data of the human stomach and to concomitantly create an anatomically correct and distensible ex-vivo gastric model. Thirty-three abdominal CT scans of human subjects were obtained and were imported into reconstruction software to generate 3D models of the stomachs. Anthropometrical data such as gastric wall thickness, gastric surface area and gastric volume were subsequently quantified. A representative 3D computer model was exported into a selective laser sintering (SLS) rapid prototyping machine to create an anatomically correct solid gastric model. Subsequently, a replica wax template of the SLS model was created. A negative mould was offset around the wax template such that the offset distance was equivalent to that of the gastric wall thickness. A silicone with similar mechanical properties to the human stomach was poured into the offset. The lost wax manufacturing technique was employed to create a hollow distensible stomach model. 3D computer gastric models were generated from the CT scans. A hollow distensible silicone ex-vivo gastric model with similar compliance to that of the human stomach was created. The anthropometrical data indicated that there is no significant relationship between BMI and gastric surface area or gastric volume. There were inter- and intra-group differences between groups with respect to gastric wall thickness. This study demonstrates that abdominal CT scans can be used to both non-invasively determine gastric anthropometrical data as well as create realistic ex-vivo stomach models.
出处 《World Journal of Gastroenterology》 SCIE CAS CSCD 2007年第9期1372-1377,共6页 世界胃肠病学杂志(英文版)
基金 Supported by the Irish Research Council for Science Engineering and Technology and by the National Development Plan
关键词 Gastric anthropometrical data Rapid prototyping Ex-vivo gastric model Computed tomography 计算机断层扫描 体外胃模型 人体测量数据 原型开发
  • 相关文献

参考文献1

二级参考文献65

  • 1[1]Gilja OH,Hausken T,Wilhelmsen I,Berstad A.Impaired accommodation of proximal stomach to a meal in functional dyspepsia.Dig Dis Sci 1996; 41:689-696
  • 2[2]Tack J,Piessevaux H,Coulie B,Caenepeel P,Janssens J.Role of impaired gastric accommodation to a meal in functional dyspepsia.Gastroenterology 1998; 115:1346-1352
  • 3[3]Oliveira RB,Troncon LE,Meneghelli UG,Padovan W,Dantas RO,de Godoy RA.Impaired gastric accommodation to distension and rapid gastric emptying in patients with Chagas' disease.Dig Dis Sci 1980; 25:790-794
  • 4[4]Undeland KA,Hausken T,Gilja OH,Aanderud S,Berstad A.Gastric meal accommodation studied by ultrasound in diabetes.Relation to vagal tone.Scand J Gastroenterol 1998; 33:236-241
  • 5[5]Tefera S,Gilja OH,Hatlebakk JG,Berstad A.Gastric accommodation studied by ultrasonography in patients with reflux esophagitis.Dig Dis Sci 2001; 46:618-625
  • 6[6]Olafsdottir E,Gilja OH,Aslaksen A,Berstad A,Fluge G.Impaired accommodation of the proximal stomach in children with recurrent abdominal pain.J Pediatr Gastroenterol Nutr 2000; 30:157-163
  • 7[7]De Schepper HU,Cremonini F,Chitkara D,Camilleri M.Assessment of gastric accommodation:overview and evaluation of current methods.Neurogastroenterol Motil2004; 16:275-285
  • 8[8]Azpiroz F,Malagelada JR.Abdominal bloating.Gastroenterology 2005; 129:1060-1078
  • 9[9]Tack J,Caenepeel P,Fischler B,Piessevaux H,Janssens J.Symptoms associated with hypersensitivity to gastric distention in functional dyspepsia.Gastroenterology 2001; 121:526-535
  • 10[10]Ropert A,des Varannes SB,Bizais Y,Roze C,Galmiche JP.Simultaneous assessment of liquid emptying and proximal gastric tone in humans.Gastroenterology 1993; 105:667-674

共引文献11

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部