摘要
[目的]做好急性驰缓性麻痹(AFP)病例监测,巩固无脊髓灰质炎(脊灰)成果。[方法]对河北省420例残留麻痹的AFP病例的流行病学、病毒学及临床特征进行分析。[结果]河北省2001～2005年AFP病例残留麻痹率为20.6%,﹤5岁的占63.1%,6～8月发病较多,服苗﹤3次的占20.7%,粪便标本肠道病毒分离率31.4%;7例分离到脊灰疫苗变异病毒。临床诊断以格林—巴利综合征最多,占47.3%。2例确诊麻痹型脊灰疫苗相关病例,1例脊灰临床符合病例。[结论]为维持无脊灰状态,应继续加强AFP病例监测,同时应加强对脊灰疫苗变异病毒致病的预防与控制。
[ Objective] To strengthen the surveillance for AFP and consolidate the achievements. [ Methods] 420 residual paralysis of AFP cases in Hebei Province were analyzed in aspects of epidemiological, virological and clinical characteristics. [Results] During 2001-2005, the rate of residual paralysis of AFP cases was 20.6%, 63.1% occurred in children under 5 years old. In most of the patients, the disease onset was from June to August. 20.7% of them were unvaccinated or not full course vaccinated （ 〈 3 times） . Enteroviruses were isolated from the stool samples of the AFP cases. Among the vaccine polioviruses, 7 were mutant strains. The diseases concerning to the residual paralysis mainly were Guillain-barre syndrome accounting for 47.3%. 2 patients were identified as vaccine-associated paralysis poliomyelitis and 1 was the clinical conformity case. [Conclusions] Strengthening the surveillance quality for AFP cases, the prevention and controlling for the poliomyelitis caused bv the mutant vaccine Doliovirus should be emphasized in order to keep the state of polio-free.
出处
《现代预防医学》
CAS
北大核心
2007年第6期1052-1054,共3页
Modern Preventive Medicine
