摘要
含酚基化合物抑制TBAS生成体系的抗氧化活性比较张尔贤,俞丽君,陈展科,肖湘(汕头大学理学院生物学系,汕头515063)Halliwell(1985)[1,2]设计了以2-脱氧-D-核糖(以下简称脱氧核糖)作为·OH自由基分子探针的反应系统,通过检测...
Deoxyribose was found to be damaged and then changed into thiobarbiturate reactive substances(TBAS)by active oxygen species from systems of Fe ̄(2+)-hypoxanthin-xanthineoxidase. The results indicated that in Fe ̄(2+)-X-XO concentrations system the TBAS production was increased when both deoxyribase and Fe ̄(2+) concentrations were increased but similar result with increase of XO was observed only within the 0. 018 U/ml range.This system was applied to determine the activity of scavenge hydroxyl radical of compound containing phenolic group with strong inhibition activity on the formation of TBAS which increases with the increase of its number of phenolic group.
出处
《生物化学杂志》
CAS
CSCD
1996年第3期374-376,共3页
关键词
生物氧化
硫代巴比妥酸
反应物
活性氧
Thiobarturate reactive substances (TBAS)
Deoxyribose
Phenolic group
Hydroxyl radical
Antioxidative activity