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生长抑素与生长激素序贯应用治疗肠外瘘的临床应用体会 被引量:9

Somatostatin and growth hormone in management of gastrointestinal fistulas
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摘要 目的研究生长抑素与生长激素在肠外瘘序贯应用治疗中的作用。探讨肠外瘘更合理的治疗方案。方法1998年1月 ̄2006年3月该院收治各类肠外瘘病人71例,其中34例单纯接受生长抑素治疗,另37例序贯应用生长抑素与生长激素治疗,对其治疗结果进行回顾性分析和总结。结果单纯生长抑素治疗后血浆白蛋白可短期内显著改善(P<0.05);平均自愈时间为(37±29.4)d,死亡5例,治愈率85%。生长抑素与生长激素序贯应用后血浆白蛋白短期内可进一步显著改善(P<0.05);平均自愈时间(31±30.7)d,较对照组显著缩短(P<0.05);死亡3例,治愈率为92%,较对照组显著提高(P<0.05)。结论生长抑素和生长激素序贯应用治疗肠外瘘,可显者缩短患者住院时间,提高肠外瘘的自行愈合率,值得临床推广应用。 [Objective] To investigate the role of somatostatin and growth hormone in the management of gastrointestinal fistulas, and furtherly explore the better treatment scheme of gostrointestinal fistulas. [Methods] There were 71 cases of gastrointestinal fistulas in our hospital from Jan, 1998 through Mar, 2006. Thirty-four of 71 patients received somatostatin only, and another 37 patients received somatostatin and growth hormone sequentially. The author respectively analyze the above materials, [Results] Thirty-four of 71 patients receiving somatostatin were cured within average (37±29,4) d with the curing rate of 85%, while another 37 patients receiving somatostatin and growth hormone sequentially were cured within average (31±30.7) days with the cure rate of 92%. [Condusion] Somatostatin and growth hormone can significantly improve the curing rate of gastrointestinal fisfula patients and reduce the treatment time.
出处 《中国现代医学杂志》 CAS CSCD 北大核心 2006年第15期2387-2388,2390,共3页 China Journal of Modern Medicine
关键词 肠外瘘 生长激素 生长抑素 Gastrointestinal fistulas growth hormone somatostatin
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参考文献5

  • 1DUDRICK ST,MARAJ AR,MCKELEVY AA.Artificial nutritional support in patients with gastrointestinal fistulas[J].World J Surg,1999,23(3):570-574.
  • 2任建安,王革非,范朝刚,王新波,汪志明,姜军,顾军,王少华,黎介寿.生长抑素与生长激素治疗肠外瘘——方法与策略的改进[J].中国实用外科杂志,2003,23(5):287-289. 被引量:52
  • 3黎介寿,任建安,尹路,韩建明.肠外瘘的治疗[J].中华外科杂志,2002,40(2):100-103. 被引量:228
  • 4REN JA,CAI XM,JIANG J,et al.Clinical investigation of gastrointestinal fistulas in the early management of a decisive operation[J].Chinese J Surgery,2001,39(3):191-193.Chinese
  • 5LI JS,REN JA,WANG XB,et al.Mechanism and clinical investigation of somatostatin and growth hormone in the management of gastrointestinal fistulas[J].Chinese J Surgery,2000,38(6):447-450.Chinese

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