摘要
目的探讨促排卵过程中卵泡发育速度与卵母细胞质量间的相关性。方法154名患者共159个体外受精-胚胎移植(IVF-ET)周期,按卵泡发育速度(v,mm/d)的分布分为A组(v<1)、B组(1≤v≤1.59)、C组(v>1.59),比较各组卵母细胞成熟度指标。结果A、B、C3组卵细胞成熟率分别为89.56%、92.45%和94.76%,优质胚胎率分别为40.85%、36.37%和37.11%,妊娠率分别为42.1%、43.1%和35.3%,卵母细胞成熟率C组高于A、B组,优质胚胎率A组高于B、C两组,但组间差异均无显著性(P>0.05),而妊娠率A、B两组明显高于C组,且B、C两组间差异有显著性(P<0.05)。结论促排卵过程中卵泡的生长速度应控制在一个最佳的范围内,因其与卵子质量和后期优质胚胎率及妊娠结局密切相关,且卵泡发育速度又可作为衡量卵泡发育潜能的一项重要指标。
Objective To investigate the relationship between follicular growth velocity and oocyte quality of ovulation induction. Methods According to the follicular growth velocity（v,mm/d）, 154 patients, 159 IVF-ET cycles ,which causes of infertility included unexplained infertility, tubal and male factor were divided into three groups： A （v 〈 1 ）, B （ 1≤ v ≤1.59 ）, C （v 〉 1.59）. Then we calculated the oocyte maturing rate, high-quality embryo rate pregnancy outcome in these groups respectively, and analyzed if there was significant deviation among the three groups. Results In group A, B and C, the oocyte maturing rates were 89.56% ,92.45% ,94.76% ; highquality embryo rates were 40. 85%, 36. 37%, 37.11% ;and pregnancy rates were 42. 1%, 43.1% , 35.3%. The maturing rate of group C was higher than that of the others. The high-quaihy embryo rate of group A was higher than that of the others, but there were no significant deviation among those groups（P 〉0. 05）. The pregnancy rate of group A and B was obviously higher than that of group C, furthermore, there were significant deviation between group B and C. Conclusion There is a close relationship between follicular growth velocity of the ovulation induction and oocyte quality, high-quality embryo rate and pregnancy outcome in the later stage. Follicular growth velocity can be seen one of the important indicators for measuring the potential of follicular development.
出处
《安徽医科大学学报》
CAS
北大核心
2006年第4期462-465,共4页
Acta Universitatis Medicinalis Anhui
关键词
受精
体外
胚胎移植
卵泡速度/生长和发育
胚胎
妊娠率
fertilization in vitro
embryo transfer
ovarian follicle/growth ＆ development
embryo
pregnancy rate
