期刊文献+

番茄红素对小鼠抗疲劳和抗氧化作用 被引量:18

Anti-fatigue and Anti-oxidation Effects of Lycopene in Mice
在线阅读 下载PDF
导出
摘要 目的研究番茄红素的抗疲劳及抗氧化作用。方法小鼠经口给予番茄红素30天后,采用负重游泳实验观察小鼠游泳死亡时间;检测血清尿素氮、肝糖原;测定血清和肝匀浆超氧化物歧化酶(SOD)活性、谷胱甘肽过氧化物酶(GSH-Px)活力、丙二醛(MDA)含量。结果给予番茄红素后,小鼠负重游泳时间明显延长,肝糖原消耗量减少,降低运动后血清尿素氮水平;升高小鼠血清和肝匀浆SOD活性及血清GSH-Px活力,降低小鼠血清和肝匀浆MDA的含量。结论番茄红素具有抗疲劳和抗氧化作用。 Objective To investigate the anti-fatigue and anti-oxidation effects of lycopene (LP). Methods Ninety mice were given randomly divided into high LP group, low LP group, and control group. LP was given orally. After 30 days, weight-loaded swimming test were performed to observe the death time. Serum urea nitrogen and glycogen were tested. The activities of superoxide dismutase ( SOD), malondialdehyde ( MDA), and glutathione peroxidase (GSH-Px) in serum and liver was measured. Results Compared with control group, LP prolonged the swimming time, increased the consumption of hepatic glycogen, and decreased the level of urea nitrogen in serum. The SOD activity and GSP-Px in LP group significantly increased and the concentrations of MDA significantly decreased. Conclusion LP can improve sporting endurance and delay fatigue, and also has antioxidative effect.
出处 《中国临床营养杂志》 CAS 2006年第3期141-143,共3页 Chinese Journal of Clinical Nutrition
基金 黑龙江省教育厅基金(10551211)
关键词 番茄红素 抗疲劳 抗氧化 lycopene antifatigue antioxidation
  • 相关文献

参考文献11

  • 1Velmurugan B,Bhuvaneswari V,Nagini S.Antiperoxidative effects of lycopene during N-methyl-N' -nitro-N-nitrosoguanidine-induced gastric carcinogenesis[J].Fitoterapia,2002,73(7-8):604-611.
  • 2潘洪志,万丽葵,那立欣,曹军.番茄红素对小鼠S_(180)肿瘤生长及免疫功能的影响[J].营养学报,2004,26(5):406-407. 被引量:11
  • 3Aust O,Ale-Agha N,Zhang L,et al.Lycopene oxidation product enhances gap junctional communication[J].Food Chem Toxicol,2003,41(10):1399-1407.
  • 4Hwang ES,Bowen PE.Effects of tomato paste extracts on cell proliferation,cell-cycle arrest and apoptosis in LNCaP human prostate cancer cells[J].Biofactors,2005,23 (2):75-84.
  • 5Velmurugan B,Mani A,Nagini S.Combination of S-allylcysteine and lycopene induces apoptosis by modulating Bcl2,Bax,Bim and caspases during experimental gastric carcinogenesis[J].Eur J Cancer Prev,2005,14 (4):387-393.
  • 6卫生部卫生监督司.保健食品功能学评价程序和检验方法[S].卫法监字[1996]第38号公布,1996,53-57.
  • 7Arab L,Stek S.Lycopene and cardiovascular disease[J].Am J Clin nutr,2000,71(6):1691s-1695s.
  • 8潘洪志,石刚,陈文华,王德才.番茄红素对大鼠体内抗氧化系统功能的影响[J].卫生研究,2003,32(5):441-442. 被引量:48
  • 9Porrini M,Riso P,Brusam.olino A,et al.Daily intake of a formulated tomato drink affects carotenoid plasma and lymphocyte concentrations and improves cellular antioxidant protection[J].Br J Nutr,2005,93(1):93-99.
  • 10Finaud J,Lac G,Filaire E.Oxidative stress:relationship with exercise and training[J].Sports Med,2006,36(4):327-358.

二级参考文献14

  • 1何金生,宗庭益.LDH释放法检测NK细胞活性的方法学研究[J].中国实验临床免疫学杂志,1996,8(2):10-13. 被引量:24
  • 2[1]GiovannucciE. Tomatoes, tomato based products,lycopene, and cancer: Review of the epidemiologic literature[J]. J Natl Cancer Inst, 1999,91:317-331.
  • 3[4]Clinton SK. Lycopene: chemistry, biology, and implications for human health and disease[J].Nutr Rev, 1998, 56:35- 51.
  • 4[5]Sharoni Y, Giron E, Rise M, et al. Effects of lycopene enriched tomato[J]. Cancer Detec Prev,1997, 21:118-123.
  • 5[6]Kim DJ, Takasuka N, Kim JM, et al. Chemprevention by lycopene of mouse lung nioplasia after combined initiation treatment with DEN, MNU, and DMH[J]. Cancer Lett, 1997, 120: 15-22.
  • 6Sies H, Stahl W. Vitamins E and C, β - carotene, and other carotenoids as antioxidants. Am J Clin Nrtr, 1995,62:1315S-1321S.
  • 7Vladimir Kmtovskikh, Makoto Asamom, Nobuo Takasuka, et al. Differential dose dependent Effects of α,β-carotenes and lycopene on gap junctional intercellular communication in rat liver in vlvo. Jpn J Cancer Bes, 1997, 88:112-114.
  • 8Rao AV, Agarwal S. Bioavailability and in vivo antioxidant properties of lycopene from tomato products and their possible role in the prevention of cancer. Nutr Cancer, 1998,31(3) : 199-203.
  • 9Agarwal S, Rao AV. Tomato lycopene and low density lipoprotein oxidation:a human dietary intervention study. Lipids, 1998, 33 (10) :981-994.
  • 10Simon Giavarotti KA, Rodrigues L, Rodrigues T, et al. Liver microsomal parameters related to oxidative stress and antioxidant systems in hyperthyroid rats subjected to acute lindane treatment. Free Radic Res, 1998,29( 1 ) : 35-42.

共引文献57

同被引文献215

引证文献18

二级引证文献121

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部