摘要
[目的]建立家鸭高脂血症模型,比较高剂量短时间和低剂量长时间两种造模方法的优劣。[方法]采用分别给予家鸭高剂量[玉米96.7%、调和油1.9%、食盐1.4%、禽用维生素0.1g(/kg·d),100g(/kg·d)]、短时间(28d)(简称模型Ⅰ组)和低剂量[配料同上,50g(/kg·d)]、长时间(49d)(简称模型Ⅱ组)方法建立模型,动态观察体质量、血清脂质、血糖。[结果]两组血清胆固醇(TC)、甘油三酯(TG)、血糖(GLU)均高于实验前,模型Ⅰ组血TG高于模型Ⅱ。[结论]两种方法均可建立高脂血症模型,而高剂量短时间造模方法从优于低剂量长时间造模方法。
[Objective] To investigate two methods to establish hyperlipidemia model and compare them which is better. [Methods] The ducks kf model Ⅰ group were fed with high-dose high glucose diet (96.7% corn,edible blend oil 1.9% ,salt 1.4%,avian vitamin 0.1 g/(kg.d), 28 days. The ducks of model Ⅱ group were fed with low-dose high glucose diet 50 g/(kg.d), 49 days. The index of body weight, blood sugar, serum grease was observed. [Results] The blood sugar,serum cholesterol and serum triglyceride of the two model groups were higher than that of before experment. [Conclusion] Two methods can replicate the hyperlipidemia model successfully, but the model I is better than the model Ⅱ.
出处
《天津中医学院学报》
2006年第1期27-28,共2页
Journal of Tianjin College of Traditional Chinese Medicine
基金
国家自然科学基金资助课题(30472210)
关键词
家鸭
高脂血症
模型
造模方法
高糖饮食
duck hyperlipidemia model
method of making model
taking more sugar in bite and sup