摘要
目的:观察症状性动脉粥样硬化性大脑中动脉狭窄患者的脑梗死模式和分布,探讨动脉粥样硬化性大脑中动脉狭窄导致脑梗死的病理生理机制。方法:回顾性分析2004-06/2005-08在北京天坛医院脑血管病抢救治疗中心治疗的50例脑血管造影证实的症状性大脑中动脉狭窄患者的MRI影像学资料,所有患者狭窄率>50%,不伴有同侧颈内动脉狭窄或闭塞,具有≥1个的动脉粥样硬化危险因素,对其脑梗死模式进行分类观察。结果:50例大脑中动脉狭窄患者的神经影像学资料分析显示,皮质下梗死最常见,其中深穿支梗死44%、内交界区梗死42%;皮质支梗死和区域性梗死各占6%和2%;散发皮质小梗死14%;外交界区梗死中前交界区梗死12%、后交界区梗死24%。结论:动脉粥样硬化性大脑中动脉狭窄可以表现为多种脑梗死模式,提示大脑中动脉狭窄导致脑梗死不同的病理生理机制。
AIM： To observe the cerebral infarction patterns and distribution of atheroselerotic middle cerebral artery stenosis, and investigate the pathophysiological mechanism of cerebral infarction induced by atherosclerotic middle cerebral artery stenosis. METHODS： The MRI data of 50 patients, who were diaguosed to have symptomatic middle cerebral artery stenosis by cerebral angiography in Beijing Tiantan Hospital between June 2004 and August 2005, were retrospectively analyzed, the stenosis rate was 〉 50% in all the patients, and they were not accompanied by ipsilateral internal carotid artery stenosis or occlusion, they all had at least 1 atherosclerotic risk factor, and their infarction patterns were categorized and observed. RESULTS： The neural imaging data of the 50 patients with middle cerebral artery stenosis showed that subcortical infarction was the most common, including 44% were deep perforator infarction and 42% were internal border-zone infarction; 6% and 2% were cortical and territorial infarction respectively; 14% were cortical spotty lesion, 12% and 24% were anterior and posterior border-zone infarction respectively. CONCLUSION： Various cerebral infarction patterns may occur in atherosclerotic middle cerebral artery stenosis, it is suggested that middle cerebral artery stenosis can lead to different pathophysiological mechanism of cerebral infarction.
出处
《中国临床康复》
CSCD
北大核心
2006年第6期100-101,共2页
Chinese Journal of Clinical Rehabilitation
