摘要
目的分析西藏不同地区儿童发硒水平,探讨大骨节病的分布特征与儿童发硒的关系。方法采集典型病区与非病区内儿童的发样,用原子荧光法测定硒。结果西藏大骨节病区与非病区儿童发硒平均值分别为(0.13±0.04)μg/g、(0.18±0.07)μg/g,二者比较差异有统计学意义(P<0.01);补硒病区与非病区的儿童发硒平均值分别为(0.28±0.03)μg/g、(0.18±0.04)μg/g,二者比较差异有统计学意义(P<0.01)。结论西藏儿童发硒普遍偏低,病区儿童发硒更低,发硒与大骨节病病情关系密切,补硒可以显著提高人体发硒水平,补硒措施是大骨节病防治的重要措施之一。
Objective To study the relationship between the selenium （Se） concentrations in child hair and the distribution of Kaschin-Beck disease（KBD） in Tibet. Methods The hair of children in typical KBD areas and non-disease areas was collected, and its Se concentrations were measured by atomic fluorescent spectrometry. Results The Se concentrations in child hair were （0.13 ± 0.04）μg/g, （0.18 ± 0.07）μg/g respectively in Tibet KBD areas and non-disease areas respectively, which were significantly different. In areas supplemented with Se in Tibet, the Se concentration of hair in KBD affected areas was higher than that in non-disease areas, being （0.28 ± 0.03）μg/g, （0.18 ± 0.04）μg/g, respectively. Conclusions There is a close relationship between the Se concentrations in hair and KBD distribution. Se supplement increase the Se concentrations of human body.Appropriate supplement of Se to human body is important to prevent KBD in Tibet.
出处
《中国地方病学杂志》
CAS
CSCD
北大核心
2006年第1期70-72,共3页
Chinese Jouranl of Endemiology
基金
国家自然科学基金资助项目(40271009)
中国科学院地理科学与资源研究所知识创新基金资助项目(CXIOG-A04-06)
关键词
大骨节病
西藏
硒
人发
Kaschin-Beck disease
Tibet
Selenium
Human hair
