摘要
目的:对利多卡因和恩丹西酮减轻异丙酚注射痛的效果进行比较,选出较佳的方案供临床使用。方法:择期手术患者89例,ASAⅠ￣Ⅱ级,按随机、双盲、对照法将患者分为三组,利多卡因组30例,恩丹西酮组29例,生理盐水对照组30例。结果:异丙酚注射痛在利多卡因组13%,在恩丹西酮组24%,对照组67%;两试验组间差异无显著性,P>0.05,试验组与对照组差异均有显著性,P<0.002。结论:两种方法都可减轻异丙酚的注射痛,但从实用性和预防术后恶心、呕吐角度考虑,恩丹西酮更佳。
Objective：To compare the effect of lidoeaine and ondansetron for the reduction of pain during injection of propofol and provide the better regimen for the clinic. Methods： 89 ASA Ⅰ - Ⅱ patients were divided into three groups in a randomized,controlled, double-blind study： group L（lidocaine group,n=30）; group O（ondansetron group,n=29）;group C（control group,n=30）. Results：The treatment groups receiving lidocaine or ondansetron had a significantly lower incidence of pain 13% and 24% respectively than the controll group 67 % （ P〈0.002 ）.There was no significant difference between two treatment groups （P〉0.05）.Conclusion：Both lidocaine and ondansetron can prevent injection pain of propofol,but ondansetron is superior to lidoeaine in the advantage of using and prevention of postoperative nausea and vomiting.
出处
《现代医药卫生》
2005年第19期2578-2579,共2页
Journal of Modern Medicine & Health
