摘要
目的:探讨精神科医生选用抗抑郁剂对抑郁症患者进行干预时优先考虑的因素。方法:调查于2004-01/10在广州市脑科医院芳村、荔湾两个门诊部完成。就诊的患者主要来自广州地区,共1496例,平均年龄45岁,女性占多数(n=923,61.7%)。调查问卷由作者自行编制,含40个条目,罗列了可能影响医生选择用药的相关因素。问卷上不记录患者姓名,但记录患者性别、年龄等。医生在问卷上注明选用的药物,每个条目只需回答是或否。医生在开药之后立即完成问卷。本调查不涉及患者隐私,基本不与患者的利益冲突,故未签署知情同意书。结果:1496例患者全部进入结果分析。最常见的影响因素依次为患者特异性的临床症状或症状谱(54.3%)、避开特定的副作用(48.9%)以及并发症的存在(46.4%)等。而停药综合征(1.2%)及药物之间的相互作用(6.3%)则很少影响医生的用药选择。结论:抑郁症患者的并发症(如合并焦虑或焦虑症)、药物副作用以及抗抑郁剂对不同症状的作用特征为精神科医生选择抗抑郁剂时的主要考虑因素。
AIM： To investigate the factors of priority consideration when psychiatrists prescribe antidepressants for depressive patients. METHODS： From January to October 2004, the survey was carried out in the Fangcun and Liwan clinics of Guangzhou Brain Hospital. Totally 1 496 patients with an average age of 45 years old, most of whom were from Guangzhou, were involved in the survey, and 923 cases （67.1%） of them were female. The 40-item inventory was compiled by the authors, listing the related factors that might affect the psychiatrists＇choice of medicine. The names of the patients were not recorded, but their gender and age were recorded. The chosen drug should be pointed out in the inventory, each item should be answered with yes or no . The inventory should be completed immediately after the prescription was given. The survey was not involved in the patients＇ secrets, and generally had no conflict with the benefits of the patients, so the agreement was not signed. RESULTS： All the 1 496 patients were involved in the analysis of results. The most common influencing factors of antidepressant choice in order were the presence of specific clinical symptoms or symptom profile （.54.3%）, the avoidance of specific side effects （48.9%）, the presence of comorbid psychiatric disorders （46.4%）, etc. While the discontinuation syndrome （1.2%） and drug-drug interaction （6.3%） seldom influenced the choice of drug. CONCLUSION： The complication of depressive patients （comorbid anxious symptoms or anxiety disorders）, side effects of drug and the action characteristics of antidepressant on different symptoms are the main factors of consideration.
出处
《中国临床康复》
CSCD
北大核心
2005年第24期6-7,共2页
Chinese Journal of Clinical Rehabilitation
