摘要
目的 :探讨发作期的精神分裂症患者症状与威斯康星卡片分类测验成绩的相关性。方法 :对新近发作、一月内未服用精神药物的精神分裂症 40例住院患者和 3 2例正常人进行了威斯康星卡片分类测验(WCST)。用阳性和阴性症状量表 (PANSS)对精神病患者进行评定 ,并对阳性、阴性和解体症状因子和威斯康星卡片分类测验结果作相关分析。结果 :精神分裂症患者WCST操作较正常人差 ,差异有显著性 (P <0 0 5 )。阴性症状因子和解体症状因子与WCST操作存在相关性 ,阳性症状因子与WCST操作不相关。结论 :精神分裂症患者在执行功能和概念化水平方面存在缺陷 ,其中解体和阴性症状可能与额叶功能障碍相关 。
Objective: The purpose of the study was to explore the correlation between clinical symptom and performances in Wisconsin Card Sorting Test (WCST) in unmedicated patients with recent onset schizophrenia Methods: Forty unmedicated schizophrenic patients with recent onset and thirty-two normal controls were studied with Wisconsin Card Sorting Test, and at the same time the patients were assessed with PANSS Multivariable correlation analysis was performed to explain relationship between symptom and WCST Results: The performance of patients with schizophrenia was significantly worse than that of the normal controls (P<0 05) The performance of WCST was correlated with disorganized symptom factors and negative symptom factors, and not with positive symptom factors Conclusion: The study suggests that the patients with schizophrenia have impairment of executive function and conceptual level,and disorganized symptoms and negative symptoms are related to frontal dysfunction, especially the former
出处
《中国心理卫生杂志》
CSSCI
CSCD
北大核心
2004年第8期580-582,共3页
Chinese Mental Health Journal
