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^(131)I-SPECT/CT融合显像诊断分化型甲状腺癌转移灶的临床价值 被引量:6

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摘要 目的评价131I-单光子发射计算机断层显像(single photon emissioncomputed tomog-raphy,SPECT)/CT融合显像鉴别诊断分化型甲状腺癌(differentiated thyroid cancer,DTC)患者转移灶的临床应用价值。方法 69例经131I治疗后的DTC患者,对131I治疗剂量全身显像(131I-whole body scan,131I-WBS)的135处放射性摄取增高灶行131I-SPECT/CT同机融合显像,对两种检查结果进行对比。最终临床诊断以病理、6个月以上的临床随访、其他影像学检查结果为依据。结果 69例131I-WBS的135处放射性摄取增高灶,经131I-SPECT/CT融合显像后均明确定位。排除了21处假阴性病灶和9处假阳性病灶1。31I-SPECT/CT融合显像鉴别转移灶优于131I-WBS(χ2=4.03,P<0.05)1。31I-WBS和131I-SPECT/CT融合显像诊断DTC转移灶的敏感性分别为70.79%,94.38%;特异性分别为76.09%,95.65%。结论 131I-SPECT/CT融合显像能更好的对放射性摄取增高灶进行精确定位和定性,是鉴别诊断DTC患者转移灶的一种较好检查方法,在临床应用中有重要价值。
出处 《四川大学学报(医学版)》 CAS CSCD 北大核心 2010年第4期734-736,共3页 Journal of Sichuan University(Medical Sciences)
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同被引文献49

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