摘要
目的:评估梅毒在化学发光免疫测定(CLIA)对梅毒的诊断价值。方法739例梅毒患者,进行CLIA试验,用TP血球凝集试验(TPHA)进行确诊。结果化学发光法检测梅毒特异性抗体的敏感度为:98.85%,特异度为:93.55%;诊断比值比为:1386.29;阳性预测值:99.56%;阴性预测值:85.96%;患病率:92.96%;阳性似然比:15.33;阴性似然比:0.01。结论 CLIA的灵敏度和特异度较高,可以作为梅毒特异性抗体筛查实验在临床上广泛应用。
Objective We evaluate the diagnostic value of that the chemiluminescence immunoassay(CLIA)test treponemal pallidum-specific antibody.Methods Serum of 739 patients were tested via CLIA and treponemal Hemagglutination(TPHA).Results The sensitivity of CLIA IS 98.85%and the specificity is 93.55,the diagnostic ratio is 1386.29,the positive predictive value is 99.56%,the negative predictive value is 85.96%,the prevalence rat is 92.96%,the positive likelihood ratio is 15.33,the negative likelihood ratio is 0.01.Conclusion The sensitivity and specificity of CLIA is high,and it can be widely used in clinical practice as a screening test for treponema pallidum-specific antibody.
作者
王静
WANG Jing(Blood Transfusion Department,The Affiliated Hospital of Southwest Medical University,Luzhou 646000,Sichuan,China)
关键词
梅毒
化学发光免疫测定
TP血球凝集试验
Syphilis
Chemiluminescence immunoassay
Treponemal Hemagglutination test
